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Fig. 3 | Clinical Epigenetics

Fig. 3

From: SMYD2 promoter DNA methylation is associated with abdominal aortic aneurysm (AAA) and SMYD2 expression in vascular smooth muscle cells

Fig. 3

a Differentially methylated CpGs in the SMYD2 gene promoter identified after bisulphite sequencing of DNA from 24 AAAs and 20 controls. b Relative gene expression levels of differentially methylated candidate genes (SMYD2, SERPINB9, IL6R and ERG) in vascular smooth muscle cells from 20 controls and 24 AAAs. c Linear relationship between gene expression and mean DNA methylation status of the differentially methylated CpGs (NC_000001.11: 214280412, 214280441, 214280507 and 214280600) in SMYD2 (n = 26 where sufficient sequencing coverage and expression data was acquired)

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