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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Integrated analyses of multi-omics reveal global patterns of methylation and hydroxymethylation and screen the tumor suppressive roles of HADHB in colorectal cancer

Fig. 4

Expression and epigenetic modification validation of HADHB in additional samples and public functional genomics data. a Expression level of HADHB determined by real-time PCR in 15 additional pairs of colorectal tumors and their adjacent normal tissues. b Expression data of HADHB from the GEO database. c, d Expression level of HADHB from the TCGA database. The results derived from different platform (c is Hiseq200 and d is G450 array) are shown respectively. e, f, Methylation and hydroxymethylation levels were determined by real-time PCR in 15 additional pairs of colorectal tumors and their adjacent normal tissues

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