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Table 3 Top 20 gene ontology (GO) terms (BP = biological process) analysed for the 1000 top-ranked CP-associated DMPs

From: Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation

GO ID

GO term

Ontology

No. of genes

DM genes

Unadjusted p value

GO:0098609

Cell-cell adhesion

BP

1091

90

8.27E-06

GO:0007156

Homophilic cell adhesion via plasma membrane adhesion molecules

BP

149

25

1.70E-05

GO:0042098

T cell proliferation

BP

157

18

2.91E-05

GO:0042129

Regulation of T cell proliferation

BP

133

16

3.28E-05

GO:0046649

Lymphocyte activation

BP

557

46

6.47E-05

GO:0032729

Positive regulation of interferon-gamma production

BP

58

10

7.55E-05

GO:0070661

Leukocyte proliferation

BP

241

23

9.24E-05

GO:0001775

Cell activation

BP

811

61

9.70E-05

GO:0050863

Regulation of T cell activation

BP

270

26

1.27E-04

GO:0022610

Biological adhesion

BP

1611

117

1.28E-04

GO:1903037

Regulation of leukocyte cell-cell adhesion

BP

284

27

1.30E-04

GO:0070663

Regulation of leukocyte proliferation

BP

187

19

1.66E-04

GO:0045321

Leukocyte activation

BP

656

50

1.93E-04

GO:0007159

Leukocyte cell-cell adhesion

BP

442

37

2.27E-04

GO:0098742

Cell-cell adhesion via plasma-membrane adhesion molecules

BP

214

27

2.32E-04

GO:0050865

Regulation of cell activation

BP

437

37

2.37E-04

GO:0016337

Single organismal cell-cell adhesion

BP

669

54

2.49E-04

GO:0032649

Regulation of interferon-gamma production

BP

85

11

2.51E-04

GO:0007155

Cell adhesion

BP

1606

115

2.56E-04

GO:0045601

Regulation of endothelial cell differentiation

BP

28

7

2.75E-04

  1. DM differentially methylated, FDR false discovery rate