Table 2 Hypermethylated genes by MethylMix criteria unique to patients who survived less than 2 years after cystectomy (references listed in Additional file 3: Table S3)

C-X-C motif chemokine ligand 6

4q13.3

[44]

Ovarian cancer [44]

ZFP42 zinc finger protein

4q35.2

Human embryonic stem cell marker [45]

Paired-like homeodomain 1

5q31.1

[46, 47]

Kidney cancer [46]

Hepatocellular cancer [47]

Radial spoke head 9 homolog

6p21.1

[48]

[49]

Bladder cancer [50]

Hepatocellular cancer

Histone cluster 1 H3 family member e

6p22.2

[51]

Glioma [51]

Sp8 transcription factor

7p21.2

Tachykinin precursor 1

7q21-q22

[46, 53, 54]

[55]

Head/neck cancer [53]

Colorectal cancer [54, 55]

Esophageal cancer [46]

Paraoxonase 3

7q21.3

[56, 57]

Bladder cancer [56]

Prostate cancer [57]

Musculin (activated B cell factor 1)

8q13.3

[58]

Lymphoma [58]

Forkhead box E1

9q22

[59]

[60]

Colorectal carcinoma [59]

Cutanous squamous cell cancer [60]

Thyroid cancer [62]

Deuterosome assembly protein 1

11q21

[63]

[64]

Thyroid carcinoma [63]

Gastric carcinoma [64]

ALX homeobox 1

12q21.31

[65]

[66]

Breast cancer [66]

Non-small cell lung cancer [65]

Ovarian cancer [67]

Solute carrier family 6 member 15

12q21.31

[68, 69]

Colorectal carcinoma [68, 69]

EP300 interacting inhibitor of differentiation 3

12q23.3

[70]

Colorectal cancer [70]

NK2 homeobox 8

14q13.3

[71]

[72, 73]

Bladder cancer [71]

Cervical cancer [73]

Esopheageal cancer [72]

Deiodinase, iodothyronine type III

14q32

[74, 75]

Lung cancer [74]

Hematologic malignancies [75]

Forkhead box C2

16q24.1

[76]

Breast cancer [76]

Heat shock protein family B (small) member 6

19q13.13

[77]

Melanoma [77]

Zinc finger protein 382

19q13.13

[78]

Esophageal cancer [78]