Skip to main content
Fig. 2 | Clinical Epigenetics

Fig. 2

From: Specific or not specific recruitment of DNMTs for DNA methylation, an epigenetic dilemma

Fig. 2

Schema of the main kinds of DNMT-including complexes. Maintaining (mainly catalyzed by DNMT1: dark blue curve) or de novo (mainly catalyzed by DNMT3A and DNMT3B: light blue curve) DNA methylation can be processed by numerous DNMT-including complexes which are either not specific (green curve) or specific (yellow curve) of particular DNA sequences. Specific complexes included polycomb proteins or transcriptional factor (TF), whereas unspecific complexes included heterochromatin readers or replication associated proteins

Back to article page