Expression profiling of chromatin-modifying enzymes and global DNA methylation in CD4+ T cells from patients with chronic HIV infection at different HIV control and progression states

Table 2 Differences in gene expression between cART recipients and noncontrollers

Gene	Median of gene expression (mRNA)		Fold up (cART-recipients vs. noncontrollers)	p value
Gene	cART recipients	Noncontrollers	Fold up (cART-recipients vs. noncontrollers)	p value
SETDB1	2.69	1.26	+ 2.15	0.033
PRMT6	0.56	0.23	+ 2.43	0.006
SUV39H1	1.87	0.61	+ 3.07	0.001
DNMT3a	2.01	0.42	+ 4.79	< 0.001
DNMT3b	4.09	0.72	+ 5.68	0.013
MBD2	1.79	0.74	+ 2.42	< 0.001
HDAC1	1.74	0.74	+ 2.35	0.002
HDAC2	1.46	0.52	+ 2.80	0.003
SIRT1	1.08	0.69	+ 1.56	0.001

ISSN: 1868-7083