Expression profiling of chromatin-modifying enzymes and global DNA methylation in CD4+ T cells from patients with chronic HIV infection at different HIV control and progression states

Table 1 Characteristics of the study participants, by group

	HIV-positive			HIV-negative	p value
	Noncontroller (without cART) (n = 32)	cART recipient (n = 26)	HIV-controller (without cART)(n = 36)	(n = 35)	p value
Age (years)^a	35 (25.25–40)	49.5 (40.75–53.75)	44 (39.5–48.5)	49 (41–53)	0.022^b
Sex (%)
Men	75	77	68	64	0.399^b
Women	25	23	32	36	0.399^b
T cell count, cells/μL^a
CD4+	554 (478–713.5)	570 (435–760)	680 (574–1132)	–	0.002
CD8+	865 (736–1148)	694 (433–910)	1031 (622–1470)	–	0.016
Viral load^a HIV-1 RNA copies/mL	26,956 (1512.75–54,579.50)	< 20	28.5 (< 20–446.75)	–	< 0.001
Duration after diagnosis (years)^a	0.16 (0.08–1)	12 (4.75–16)	14 (7.5–19)	–	< 0.001

cART combination antiretroviral therapy, NA not applicable, NS not significant
^aData are median (interquartile range, IQR)
^bData denote results of comparisons between HIV-positive vs. HIV-negative

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