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Table 1 Characteristics of the study participants, by group

From: Expression profiling of chromatin-modifying enzymes and global DNA methylation in CD4+ T cells from patients with chronic HIV infection at different HIV control and progression states

  HIV-positive HIV-negative p value
Noncontroller (without cART) (n = 32) cART recipient (n = 26) HIV-controller (without cART)(n = 36) (n = 35)
Age (years)a 35 (25.25–40) 49.5 (40.75–53.75) 44 (39.5–48.5) 49 (41–53) 0.022b
Sex (%)
 Men 75 77 68 64 0.399b
 Women 25 23 32 36
T cell count, cells/μLa
 CD4+ 554 (478–713.5) 570 (435–760) 680 (574–1132) 0.002
 CD8+ 865 (736–1148) 694 (433–910) 1031 (622–1470) 0.016
Viral loada HIV-1 RNA copies/mL 26,956 (1512.75–54,579.50) < 20 28.5 (< 20–446.75) < 0.001
Duration after diagnosis (years)a 0.16 (0.08–1) 12 (4.75–16) 14 (7.5–19) < 0.001
  1. cART combination antiretroviral therapy, NA not applicable, NS not significant
  2. aData are median (interquartile range, IQR)
  3. bData denote results of comparisons between HIV-positive vs. HIV-negative