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Table 7 RBBP8 biomarker performance

From: Promoter methylation of DNA damage repair (DDR) genes in human tumor entities: RBBP8/CtIP is almost exclusively methylated in bladder cancer

Cutoff

Specificity (%)

Sensitivity (%)

AUC

p value

Control group

RBBP8 CpG #7 and #8

 14.25

100

25.0

0.730

0.002

Benign

 1.25

90.9

51.9

 14.25

96.1

25.0

0.686

0.001

Malignant

 4.00

90.2

40.4

RBBP8 CpG all

 11.75

100

26.9

0.660

0.030

Benign

 0.69

77.3

51.9

 11.75

96.1

26.9

0.649

0.009

Malignant

 3.94

90.2

38.5