Skip to main content

Table 1 Clinical characteristics of subjects at the Untrained, Trained, and Detrained state

From: Endurance training remodels sperm-borne small RNA expression and methylation at neurological gene hotspots

A

 Cohort used for DNA CpG analyses, n = 12

 

Untrained

Trained

Detrained

  Age – years

22 (18 a 27)

23 (18 a 27)

23 (19 a 28)

  Weight - kg

79.0 (63.7 a 105.8)

77.5 (63.7 a 102.2)

79.1 (62.6 a 105.3)

  Body mass index - kg/m2

22.8 (19.5 a 27.6)

22.9 (19.6 a 26.7)

23.1 (19.2 a 27.4)

  Waist – cm

87 (79 a 90)

79* (73 a 87)

80.8# (72.6 a 92.6)

  Hip – cm

93 (88 a 104)

89* (82 a 99)

90# (82 a 101)

  Waist/Hip

0.92 (0.88 a 0.99)

0.88 (0.83 a 0.96)

0.91 (0.86 a 0.97)

  VO2

2780 (3585 a 4469)

4440* (3319 a 5793)

3971 (2763 a 4766)

  VO2/kg

44.1 (39.7 a 53.9)

56.2* (48.4 a 65.2)

51.2 (38.3 a 55.5)

  Glucose (fasting) – mmol/l

4.8 (4.3 a 5.4)

4.8 (4.4 a 5.7)

4.7 (4.3 a 5.3)

  Insulin – pmol/l

55 (31 a 106)

51 (25 a 117)

57 (27 a 80)

  HOMA-IR

1.85 (1.11 a 4.03)

1.9 (0.9 a 4.9)

1.9 (0.9 a 2.9)

  HbA1c - %

32 (26 a 38)

33 (28 a 36)

31# (23 a 36)

  Plasma cholesterol (total) – mmol/l

4.2 (3.4 a 5.6)

4.0 (3.0 a 4.8)

4.3 (3.4 a 5.4)

  Low density lipoprotein – mmol/l

2.3 (1.9 a 3.3)

2.4 (1.8 a 3.0)

2.6 (1.8 a 3.4)

  High density lipoprotein – mmol/l

1.4 (1.0 a 1.7)

1.4 (1.1 a 1.6)

1.3 (1.0 a 1.8)

  Triglyceride – mmol/l

1.0 (0.6 a 1.5)

0.9 (0.6 a 1.7)

0.9 (0.5 a 1.8)

  C-reactive protein – mg/l

1.0 (1.0 a 3.0)

1.0 (1.0 a 1.0)

1.0 (1.0 a 2.5)

  Leukocytes – ×  109/l

6.0 (3.3 a 7.1)

5.4 (4.3 a 6.7)

5.4 (4.1 a 6.5)

B

 Cohort used for sRNA analyses, n = 6

   
 

Untrained, n = 6

Trained, n = 6

Detrained, n = 6

  Age – years

23 (18.1 a 26.9)

23 (18.1 a 26.9)

24 (19 a 27)

  Weight - kg

79.8 (64.4 a 88.5)

79.8 (64.3 a 86.2)

81.2 (63.0 a 89.7)

  Body mass index - kg/m2

22.8 (19.8 a 24.8)

22.7 (19.8 a 24.1)

22.9 (19.4 a 24.0)

  Waist – cm

88.5 (78.6 a 95.2)

79.2* (72.4 a 88)

80.5 (72.4 a 93.9)

  Hip – cm

92 (88.2 a 99.8)

90.2 (85.4 a 97.2)

91 (83 a 99)

  Waist/Hip

0.9 (0.9 a 1)

0.9 (0.8 a 0.9)

0.91 (0.83 a 0.95)

  VO2

3736 (2766 a 4460)

4221 (3459 a 5167)

3830 (2766 a 4621)

  VO2/kg

45 (40.1 a 53.8)

52.6 (48.1 a 63.5)

50.7 (37.4 a 55.5)

  Glucose (fasting) – mmol/l

4.8 (4.3 a 5.4)

4.8 (4.6 a 5.8)

4.7 (4.4 a 5.3)

  Insulin – pmol/l

80 (54.4 a 107.5)

56 (41.4 a 121.4)

58 (45 a 81)

  HOMA-IR

2.9 (1.8 a 4.1)

2 (1.5 a 5.2)

2.0 (1.7 a 2.9)

  HbA1c - %

33.5 (29.2 a 38.8)

33.5 (28.1 a 36)

30# (26 a 37)

  Plasma cholesterol (total) – mmol/l

4.6 (3.9 a 5.8)

4.1 (3.6 a 4.8)

5.1 (4.3 a 5.8)

  Low density lipoprotein – mmol/l

2.6 (2.1 a 3.6)

2.5 (1.9 a 3.2)

1.4 (1.0 a 1.9)

  High density lipoprotein – mmol/l

1.3 (1 a 1.5)

1.4 (1 a 1.5)

2.9 (2.4 a 4.1)

  Triglyceride – mmol/l

1.2 (0.9 a 1.6)

1.1 (0.7 a 1.7)

1.1 (0.8 a 1.9)

  C-reactive protein – mg/l

1 (1 a 2.8)

1 (1 a 1)

1.0 (1.0 a 2.9)

  Leukocytes – Ă— 109/l

6.1 (3.4 a 8)

6.1 (4.2 a 7.7)

5.4 (4.4 a 11.2)

  1. A Subjects studied for DNA methylation. B Subjects studied for sRNA expression. HOMA-IR: Homeostatic Model Assessment of Insulin Resistance. Results are medians with 2.5 and 97.5 percentiles. Differences between time points were determined using a paired t test or a Wilcoxon signed rank (Insulin and HOMA-IR in both tables and Triglyceride in Table 1a) and are Holm-Bonferroni corrected. Age and C-reactive protein were not tested. *P < 0.05 Untrained vs. Trained, #P < 0.05 Untrained vs. Detrained