Table 3 Most of the integration events were located in previously reported hot spots in the human genome
Gene | Locus | Frequency | Virus breakpoint sites |
|---|---|---|---|
MYC | 8q24 | 6 | nt3467, nt3392, nt1886, nt1960, nt2210 |
SLC7A1 | 1p32.3 | 2 | nt3467, nt3371 |
MYF5 | 12q21 | 1 | nt5619 |
SLITRK5 | 3q26.1 | 2 | nt3867, nt1974 |
RAB39A | 10q26.11 | 2 | nt5619, nt5311 |
CD53 | 1p13.3 | 2 | nt5834, nt2663 |
TMEM219 | 16p11.2 | 2 | nt5320, nt5365 |
BRCA1 | 17q21 | 3 | nt3467, nt1869, nt2331 |
ZFP91 | 19q12 | 5 | nt5812, nt5789, nt1890, nt2759, nt2860 |
LOC642587 | 1q32.2 | 1 | nt5365 |
SLIT3 | 5q35.1 | 1 | nt3272 |
ZNF595 | 4p16.3 | 3 | nt5623, nt5521, nt2601 |
CD34 | 1q32.2 | 2 | nt5619, nt2775 |
CDK14 | 7q21.13 | 2 | nt5796, nt1903 |
RAB9B | Xq22.2 | 1 | nt5353 |
STK24 | 13q32 | 2 | nt2254, nt2684 |
SH3BP2 | 4p16 | 1 | nt5296 |
SLITRK2 | Xq27.3 | 4 | nt5794, nt5321, nt5561, nt2117 |
TNFAIP2 | 14q32.3 | 2 | nt2735, nt2115 |
ZNF519 | 18p11 | 2 | nt5826, nt2260 |
TNFSF15 | 9q32 | 1 | nt5207 |
SLC4A3 | 2q35 | 2 | nt2789, nt2334 |
MYO1H | 12q24 | 1 | nt5897 |
SPANXN1 | Xq27.3 | 2 | nt2677, nt2892 |
MRPL17 | 11p15.4 | 2 | nt1908, nt2741 |
OR2AG1 | 11p15.4 | 2 | nt5783, nt2332 |
FANCC | 9q22 | 2 | nt3467, nt2467 |
SLC1A3 | 5p13.2 | 1 | nt2887 |
LRP1B | 2q21 | 2 | nt5811, nt1899 |
SOX6 | 11p15.2 | 2 | nt2434, nt2561 |
LOC401097 | 3q25 | 1 | nt3592 |
SLC13A1 | 7q31 | 1 | nt1899 |
MYBPC1 | 12q23 | 1 | nt2770 |
SLC38A4 | 12q13 | 2 | nt1889, nt2654 |
CYP7A1 | 8q12 | 2 | nt2735, nt1899 |
ATPBD4 | 15q14 | 2 | nt2017, nt2229 |
SOX2 | 3q26 | 3 | nt3226, nt2115, nt2095 |
CADM2 | 3p12 | 3 | nt2735, nt1899, nt2833 |
LOC728410 | 10q26 | 2 | nt3309, nt3596 |
PRKX | Xp22 | 3 | nt5964, nt5790 |
GAP43 | 3q13 | 1 | nt2735 |
TFPI | 2q32 | 2 | nt3584, nt2607 |
PPP2R3A | 3q22 | 2 | nt2774, nt2601 |
MCTP1 | 5q15 | 1 | nt3206 |
HLF | 17q22 | 2 | nt5934, nt5821 |
CLTCL1 | 22q11 | 1 | nt3201 |
LPPR4 | 1p21 | 2 | nt5797, nt2735 |
SLC5A3 | 21q22 | 1 | nt1899 |
ZNF165 | 6p22 | 1 | nt3298 |
STK24 | 13q32.2 | 1 | nt2392 |
C5orf39 | 5p12 | 1 | nt1899 |
PCDH17 | 13q21 | 1 | nt3577 |
STK11 | 19p13.3 | 1 | nt1923 |
TMEM26 | 10q21 | 1 | nt3318 |
HLA-E | 6p22 | 1 | nt5867 |
FAM82A1 | 2p22.2 | 1 | nt2397 |
CD44 | 11p13 | 2 | nt3215 |
FAM131C | 1p36.13 | 1 | nt6854 |
SLBP | 4p16.3 | 1 | nt2662 |
SOX17 | 8q12.1 | 1 | nt2735 |
PRKCA | 17q24.2 | 1 | nt3596 |
PAH | 12q23.2 | 1 | nt7458 |