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Table 5 Characteristics of case and control subgroups in PBL subtype analysis

From: Genomic 5-mC contents in peripheral blood leukocytes were independent protective factors for coronary artery disease with a specific profile in different leukocyte subtypes

Clinical data Control (n = 50) Casea (n = 50) P
Age (years) 64 ± 9.5 62 ± 9.9 0.248b
Male gender 26 (52%) 27 (54%) 0.84c
Hypertension 16 (32%) 31 (62%) 0.003 c
Hyperlipidemia 9 (18%) 19 (38%) 0.026 c,d
Diabetes 10 (20%) 21 (42%) 0.017 c
PBLs counts (10 9 /L) 5.48 (4.56~6.65) 6.63 (5.63~9.28) 0.001 e
Neutrophil (%) 59.22 ± 10.55 66.01 ± 11.45 0.003 b
Lymphocyte (%) 30.28 ± 8.46 24.08 ± 9.72 0.001 b
Monocyte (%) 7.72 ± 2.78 7.47 ± 2.47 0.625b
5-mC contents (5-mC/C %) 4.11 ± 0.73 3.75 ± 0.76 0.017 b
5-hmC contents (5-hmC/C %) 0.0163 ± 0.0052 0.0191 ± 0.0048 0.005 b
DNMT1 expressions 0.0084 ± 0.0058 0.0064 ± 0.0029 0.006 b
  1. Data are presented as mean ± SD or as median (inter-quartile range). Italic letters show the significant associations and their P values
  2. aThe CAD patients are consists of 14 (28%) myocardial infarction and 36 (72%) angina pectoris, respectively
  3. bStudent’s t test
  4. cχ2 test
  5. dMost of the CAD patients with hyperlipidemia were under anti-hyperlipidemia therapy in the case group
  6. eMann-Whitney U test