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Table 3 Associations between global 5-mC contents and CAD

From: Genomic 5-mC contents in peripheral blood leukocytes were independent protective factors for coronary artery disease with a specific profile in different leukocyte subtypes

  Odds ratio (95% CI) P value
Not adjusted 0.397 (0.308, 0.512) 1.15 × 10−12
Adjusted for age and sex 0.393 (0.304, 0.507) 8.40 × 10−13
Plus histories of HT, HL, and DM 0.388 (0.295, 0.511) 1.66 × 10−11
Plus PBL counts 0.355 (0.262, 0.481) 2.54 × 10− 11
Plus PBL classifications 0.325 (0.237, 0.445) 2.62 × 10−12
  1. The OR value represents altered risk of CAD odds per unit change in global 5-mC contents. Odds ratio less than 1 indicates that the independent factor (i.e., global 5-mC contents) is a protective factor