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Table 1 Characteristics of cases and controls in association analysis

From: Genomic 5-mC contents in peripheral blood leukocytes were independent protective factors for coronary artery disease with a specific profile in different leukocyte subtypes

Clinical data Control (n = 270) Casea (n = 265) P
Age (years) 57.72 ± 10 58.03 ± 9.5 0.716b
Male gender 150 (56%) 154 (58%) 0.601c
Hypertension 93 (34%) 169 (64%) < 0.001 c
Hyperlipidemia 63 (23%) 100 (38%) < 0.001 c
Diabetes 66 (24%) 106 (40%) < 0.001 c
TC (mmol/L) 4.36 ± 0.55 4.37 ± 1.07 0.832b,d
TG (mmol/L) 1.01 (0.77~1.28) 1.35 (1.00~1.92) < 0.001 d,e
HDL-C (mmol/L) 1.26 (1.13~1.42) 1.10 (0.94~1.34) < 0.001 d,e
LDL-C (mmol/L) 2.57 ± 0.36 2.43 ± 0.88 0.017 b,d
FBG (mmol/L) 4.71 (4.35~5.15) 5.84 (5.31~6.87) < 0.001 e
PBLs counts (10 9 /L) 5.30 (4.60~6.29) 6.58 (5.33~7.92) < 0.001 e
PBLs classifications (PBMCs %) 40.31 ± 8.11 34.48 ± 10.16 < 0.001 b
5-mC contents (5-mC/C %) 4.42 ± 0.87 3.90 ± 0.63 < 0.001 b,f
  1. Data are presented as mean ± SD or as median (inter-quartile range). Italic letters show the significant associations and their P values. PBL classifications were calculated by percentages of PBMCs in PBLs
  2. aThe CAD patients are consists of 71 (27%) myocardial infarction and 194 (73%) angina pectoris, respectively
  3. bStudent’s t test
  4. cχ2 test
  5. dMost of the CAD patients with hyperlipidemia were under anti-hyperlipidemia therapy in the case group
  6. eMann-Whitney U test
  7. fP = 1.10 × 10− 14