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Fig. 4 | Clinical Epigenetics

Fig. 4

From: DNA methylation alterations in iPSC- and hESC-derived neurons: potential implications for neurological disease modeling

Fig. 4

Comparative analysis of DNA methylation in pluripotent cells and neural derivatives. In silico PCA of 450 K-based DNA methylation data from pluripotent stem cells and neural cells generated from fibroblast-derived iPSC [11] and H9 hESC [15] as well as isogenic I3 hESC- and iPSC. Fibroblast-derived iPSC originate from iPD and LRRK2 patients as well as healthy control donors

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