Regression coefficient (95% CI) and P values2 | |||
---|---|---|---|
Epigenetic age acceleration measures, per year increase | Percent of time spent sedentary | Logged average number of steps per day | Logged average number of sit-to-stand transitions per day |
Extrinsic epigenetic age acceleration | |||
Adjusted for sex and age | 0.181 (− 0.025, 0.387) P = 0.085/P corrected = 0.187 | − 0.100 (− 0.008, − 0.001) P = 0.027/P corrected = 0.149 | − 0.001 (− 0.006, 0.004) P = 0.671/P corrected = 0.671 |
Multivariable-adjusted1 | 0.109 (− 0.093, 0.310) P = 0.289/P corrected = 0.397 | − 0.007 (− 0.015, 0.001) P = 0.083/P corrected = 0.187 | − 0.003 (− 0.006, 0.005) P = 0.922/P corrected = 0.920 |
Intrinsic epigenetic age acceleration | |||
Adjusted for sex and age | − 0.105 (− 0.340, 0.129) P = 0.379/P corrected = 0.429 | − 0.005 (− 0.015, 0.004) P = 0.273/P corrected = 0.397 | 0.006 (0.0001, 0.012) P = 0.049/P corrected = 0.181 |
Multivariable-adjusted1 | − 0.146 (− 0.371, 0.079) P = 0.203/P corrected = 0.372 | − 0.004 (− 0.013, 0.005) P = 0.390/P corrected = 0.429 | 0.007 (0.001, 0.013) P = 0.027/P corrected = 0.149 |