TY - JOUR AU - Siegel, R. L. AU - Miller, K. D. AU - Jemal, A. PY - 2015 DA - 2015// TI - Cancer statistics, 2015 JO - CA Cancer J Clin VL - 65 UR - https://doi.org/10.3322/caac.21254 DO - 10.3322/caac.21254 ID - Siegel2015 ER - TY - STD TI - Portillo K, Perez-Rodas N, Garcia-Olive I, Guasch-Arriaga I, Centeno C, Serra P, et al. Lung cancer in patients with combined pulmonary fibrosis and emphysema and idiopathic pulmonary fibrosis. A descriptive study in a Spanish series. Arch Bronconeumol. 2016; https://doi.org/10.1016/j.arbres.2016.10.004. ID - ref2 ER - TY - JOUR AU - Alvarez, F. V. AU - Trueba, I. M. AU - Sanchis, J. B. AU - Lopez-Rodo, L. M. AU - Rodriguez Suarez, P. M. AU - de Cos Escuin, J. S. PY - 2016 DA - 2016// TI - Recommendations of the Spanish Society of Pneumology and Thoracic Surgery on the diagnosis and treatment of non-small-cell lung cancer JO - Arch Bronconeumol VL - 52 ID - Alvarez2016 ER - TY - STD TI - Gonzalez J, de Torres JP. Lung cancer and emphysema. Arch Bronconeumol. 2016; https://doi.org/10.1016/j.arbres.2016.07.010. ID - ref4 ER - TY - JOUR AU - Sanchez-Salcedo, P. AU - Berto, J. AU - de Torres, J. P. AU - Campo, A. AU - Alcaide, A. B. AU - Bastarrika, G. PY - 2015 DA - 2015// TI - Lung cancer screening: fourteen year experience of the Pamplona early detection program (P-IELCAP) JO - Arch Bronconeumol VL - 51 UR - https://doi.org/10.1016/j.arbres.2014.09.019 DO - 10.1016/j.arbres.2014.09.019 ID - Sanchez-Salcedo2015 ER - TY - JOUR AU - Sanchez-Salcedo, P. AU - Wilson, D. O. AU - de Torres, J. P. AU - Weissfeld, J. L. AU - Berto, J. AU - Campo, A. PY - 2015 DA - 2015// TI - Improving selection criteria for lung cancer screening. The potential role of emphysema JO - Am J Respir Crit Care Med VL - 191 UR - https://doi.org/10.1164/rccm.201410-1848OC DO - 10.1164/rccm.201410-1848OC ID - Sanchez-Salcedo2015 ER - TY - JOUR AU - de CJ, S. AU - Hernandez, J. H. AU - Lopez, M. F. AU - Sanchez, S. P. AU - Gratacos, A. R. AU - Porta, R. R. PY - 2011 DA - 2011// TI - SEPAR guidelines for lung cancer staging JO - Arch Bronconeumol VL - 47 ID - de CJ2011 ER - TY - JOUR AU - Barreiro, E. AU - Fermoselle, C. AU - Mateu-Jimenez, M. AU - Sanchez-Font, A. AU - Pijuan, L. AU - Gea, J. PY - 2013 DA - 2013// TI - Oxidative stress and inflammation in the normal airways and blood of patients with lung cancer and COPD JO - Free Radic Biol Med VL - 65 UR - https://doi.org/10.1016/j.freeradbiomed.2013.08.006 DO - 10.1016/j.freeradbiomed.2013.08.006 ID - Barreiro2013 ER - TY - JOUR AU - Gupta, A. AU - Srivastava, S. AU - Prasad, R. AU - Natu, S. M. AU - Mittal, B. AU - Negi, M. P. PY - 2010 DA - 2010// TI - Oxidative stress in non-small cell lung cancer patients after chemotherapy: association with treatment response JO - Respirology VL - 15 UR - https://doi.org/10.1111/j.1440-1843.2009.01703.x DO - 10.1111/j.1440-1843.2009.01703.x ID - Gupta2010 ER - TY - JOUR AU - Masri, F. A. AU - Comhair, S. A. AU - Koeck, T. AU - Xu, W. AU - Janocha, A. AU - Ghosh, S. PY - 2005 DA - 2005// TI - Abnormalities in nitric oxide and its derivatives in lung cancer JO - Am J Respir Crit Care Med VL - 172 UR - https://doi.org/10.1164/rccm.200411-1523OC DO - 10.1164/rccm.200411-1523OC ID - Masri2005 ER - TY - STD TI - Mateu-Jimenez M, Sanchez-Font A, Rodriguez-Fuster A, Aguilo R, Pijuan L, Fermoselle C, et al. Redox imbalance in lung cancer of patients with underlying chronic respiratory conditions. Mol Med. 2016; https://doi.org/10.2119/molmed.2015.00199. Pubmed PMID: PMC5004710 ID - ref11 ER - TY - JOUR AU - Cho, W. C. AU - Kwan, C. K. AU - Yau, S. AU - So, P. P. AU - Poon, P. C. AU - Au, J. S. PY - 2011 DA - 2011// TI - The role of inflammation in the pathogenesis of lung cancer JO - Expert Opin Ther Targets VL - 15 UR - https://doi.org/10.1517/14728222.2011.599801 DO - 10.1517/14728222.2011.599801 ID - Cho2011 ER - TY - JOUR AU - O'Byrne, K. J. AU - Dalgleish, A. G. PY - 2001 DA - 2001// TI - Chronic immune activation and inflammation as the cause of malignancy JO - Br J Cancer VL - 85 UR - https://doi.org/10.1054/bjoc.2001.1943 DO - 10.1054/bjoc.2001.1943 ID - O'Byrne2001 ER - TY - JOUR AU - Mateu-Jimenez, M. AU - Curull, V. AU - Pijuan, L. AU - Sanchez-Font, A. AU - Rivera-Ramos, H. AU - Rodriguez-Fuster, A. PY - 2017 DA - 2017// TI - Systemic and tumor Th1 and Th2 inflammatory profile and macrophages in lung cancer: influence of underlying chronic respiratory disease JO - J Thorac Oncol VL - 12 UR - https://doi.org/10.1016/j.jtho.2016.09.137 DO - 10.1016/j.jtho.2016.09.137 ID - Mateu-Jimenez2017 ER - TY - JOUR AU - Breitling, L. P. AU - Yang, R. AU - Korn, B. AU - Burwinkel, B. AU - Brenner, H. PY - 2011 DA - 2011// TI - Tobacco-smoking-related differential DNA methylation: 27K discovery and replication JO - Am J Hum Genet VL - 88 UR - https://doi.org/10.1016/j.ajhg.2011.03.003 DO - 10.1016/j.ajhg.2011.03.003 ID - Breitling2011 ER - TY - JOUR AU - Gao, X. AU - Jia, M. AU - Zhang, Y. AU - Breitling, L. P. AU - Brenner, H. PY - 2015 DA - 2015// TI - DNA methylation changes of whole blood cells in response to active smoking exposure in adults: a systematic review of DNA methylation studies JO - Clin Epigenetics VL - 7 UR - https://doi.org/10.1186/s13148-015-0148-3 DO - 10.1186/s13148-015-0148-3 ID - Gao2015 ER - TY - JOUR AU - Zhang, Y. AU - Elgizouli, M. AU - Schottker, B. AU - Holleczek, B. AU - Nieters, A. AU - Brenner, H. PY - 2016 DA - 2016// TI - Smoking-associated DNA methylation markers predict lung cancer incidence JO - Clin Epigenetics VL - 8 UR - https://doi.org/10.1186/s13148-016-0292-4 DO - 10.1186/s13148-016-0292-4 ID - Zhang2016 ER - TY - JOUR AU - Sundar, I. K. AU - Mullapudi, N. AU - Yao, H. AU - Spivack, S. D. AU - Rahman, I. PY - 2011 DA - 2011// TI - Lung cancer and its association with chronic obstructive pulmonary disease: update on nexus of epigenetics JO - Curr Opin Pulm Med VL - 17 UR - https://doi.org/10.1097/MCP.0b013e3283477533 DO - 10.1097/MCP.0b013e3283477533 ID - Sundar2011 ER - TY - JOUR AU - Wang, S. AU - Wang, Z. PY - 2013 DA - 2013// TI - Epigenetic aberrant methylation of tumor suppressor genes in small cell lung cancer JO - J Thorac Dis VL - 5 ID - Wang2013 ER - TY - JOUR AU - Chen, C. AU - Hua, H. AU - Han, C. AU - Cheng, Y. AU - Cheng, Y. AU - Wang, Z. PY - 2015 DA - 2015// TI - Prognosis value of MGMT promoter methylation for patients with lung cancer: a meta-analysis JO - Int J Clin Exp Pathol VL - 8 ID - Chen2015 ER - TY - JOUR AU - Suzuki, M. AU - Wada, H. AU - Yoshino, M. AU - Tian, L. AU - Shigematsu, H. AU - Suzuki, H. PY - 2010 DA - 2010// TI - Molecular characterization of chronic obstructive pulmonary disease-related non-small cell lung cancer through aberrant methylation and alterations of EGFR signaling JO - Ann Surg Oncol VL - 17 UR - https://doi.org/10.1245/s10434-009-0739-3 DO - 10.1245/s10434-009-0739-3 ID - Suzuki2010 ER - TY - JOUR AU - Wauters, E. AU - Janssens, W. AU - Vansteenkiste, J. AU - Decaluwe, H. AU - Heulens, N. AU - Thienpont, B. PY - 2015 DA - 2015// TI - DNA methylation profiling of non-small cell lung cancer reveals a COPD-driven immune-related signature JO - Thorax VL - 70 UR - https://doi.org/10.1136/thoraxjnl-2015-207288 DO - 10.1136/thoraxjnl-2015-207288 ID - Wauters2015 ER - TY - JOUR AU - Houghton, A. M. PY - 2013 DA - 2013// TI - Mechanistic links between COPD and lung cancer JO - Nat Rev Cancer VL - 13 UR - https://doi.org/10.1038/nrc3477 DO - 10.1038/nrc3477 ID - Houghton2013 ER - TY - JOUR AU - Van Pottelberge, G. R. AU - Mestdagh, P. AU - Bracke, K. R. AU - Thas, O. AU - van Durme, Y. M. AU - Joos, G. F. PY - 2011 DA - 2011// TI - MicroRNA expression in induced sputum of smokers and patients with chronic obstructive pulmonary disease JO - Am J Respir Crit Care Med VL - 183 UR - https://doi.org/10.1164/rccm.201002-0304OC DO - 10.1164/rccm.201002-0304OC ID - Van Pottelberge2011 ER - TY - JOUR AU - Liloglou, T. AU - Bediaga, N. G. AU - Brown, B. R. AU - Field, J. K. AU - Davies, M. P. PY - 2014 DA - 2014// TI - Epigenetic biomarkers in lung cancer JO - Cancer Lett VL - 342 UR - https://doi.org/10.1016/j.canlet.2012.04.018 DO - 10.1016/j.canlet.2012.04.018 ID - Liloglou2014 ER - TY - JOUR AU - Miravitlles, M. AU - Soler-Cataluna, J. J. AU - Calle, M. AU - Molina, J. AU - Almagro, P. AU - Quintano, J. A. PY - 2017 DA - 2017// TI - Spanish guidelines for management of chronic obstructive pulmonary disease (GesEPOC) 2017. Pharmacological treatment of stable phase JO - Arch Bronconeumol VL - 53 UR - https://doi.org/10.1016/j.arbres.2017.03.018 DO - 10.1016/j.arbres.2017.03.018 ID - Miravitlles2017 ER - TY - JOUR AU - Vogelmeier, C. F. AU - Criner, G. J. AU - Martinez, F. J. AU - Anzueto, A. AU - Barnes, P. J. AU - Bourbeau, J. PY - 2017 DA - 2017// TI - Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease 2017 report: GOLD executive summary JO - Arch Bronconeumol VL - 53 UR - https://doi.org/10.1016/j.arbres.2017.02.001 DO - 10.1016/j.arbres.2017.02.001 ID - Vogelmeier2017 ER - TY - JOUR AU - Blandino, G. AU - Fazi, F. AU - Donzelli, S. AU - Kedmi, M. AU - Sas-Chen, A. AU - Muti, P. PY - 2014 DA - 2014// TI - Tumor suppressor microRNAs: a novel non-coding alliance against cancer JO - FEBS Lett VL - 588 UR - https://doi.org/10.1016/j.febslet.2014.03.033 DO - 10.1016/j.febslet.2014.03.033 ID - Blandino2014 ER - TY - JOUR AU - Miravitlles, M. PY - 2016 DA - 2016// TI - What was the impact of the Spanish COPD guidelines (GesEPOC) and how can they be improved? JO - Arch Bronconeumol VL - 52 UR - https://doi.org/10.1016/j.arbres.2015.04.001 DO - 10.1016/j.arbres.2015.04.001 ID - Miravitlles2016 ER - TY - JOUR AU - Puig-Vilanova, E. AU - Ausin, P. AU - Martinez-Llorens, J. AU - Gea, J. AU - Barreiro, E. PY - 2014 DA - 2014// TI - Do epigenetic events take place in the vastus lateralis of patients with mild chronic obstructive pulmonary disease? JO - PLoS One VL - 9 UR - https://doi.org/10.1371/journal.pone.0102296 DO - 10.1371/journal.pone.0102296 ID - Puig-Vilanova2014 ER - TY - JOUR AU - Puig-Vilanova, E. AU - Rodriguez, D. A. AU - Lloreta, J. AU - Ausin, P. AU - Pascual-Guardia, S. AU - Broquetas, J. PY - 2015 DA - 2015// TI - Oxidative stress, redox signaling pathways, and autophagy in cachectic muscles of male patients with advanced COPD and lung cancer JO - Free Radic Biol Med VL - 79 UR - https://doi.org/10.1016/j.freeradbiomed.2014.11.006 DO - 10.1016/j.freeradbiomed.2014.11.006 ID - Puig-Vilanova2015 ER - TY - JOUR AU - Puig-Vilanova, E. AU - Martinez-Llorens, J. AU - Ausin, P. AU - Roca, J. AU - Gea, J. AU - Barreiro, E. PY - 2015 DA - 2015// TI - Quadriceps muscle weakness and atrophy are associated with a differential epigenetic profile in advanced COPD JO - Clin Sci (Lond) VL - 128 UR - https://doi.org/10.1042/CS20140428 DO - 10.1042/CS20140428 ID - Puig-Vilanova2015 ER - TY - STD TI - Chacon-Cabrera A, Gea J, Barreiro E. Short- and long-term hindlimb immobilization and reloading: profile of epigenetic events in gastrocnemius. J Cell Physiol. 2016; https://doi.org/10.1002/jcp.25635. ID - ref33 ER - TY - JOUR AU - Puig-Vilanova, E. AU - Aguilo, R. AU - Rodriguez-Fuster, A. AU - Martinez-Llorens, J. AU - Gea, J. AU - Barreiro, E. PY - 2014 DA - 2014// TI - Epigenetic mechanisms in respiratory muscle dysfunction of patients with chronic obstructive pulmonary disease JO - PLoS One VL - 9 UR - https://doi.org/10.1371/journal.pone.0111514 DO - 10.1371/journal.pone.0111514 ID - Puig-Vilanova2014 ER - TY - JOUR AU - Mateu-Jimenez, M. AU - Fermoselle, C. AU - Rojo, F. AU - Mateu, J. AU - Pena, R. AU - Urtreger, A. J. PY - 2016 DA - 2016// TI - Pharmacological approaches in an experimental model of non-small cell lung cancer: effects on tumor biology JO - Curr Pharm Des VL - 22 UR - https://doi.org/10.2174/1381612822666160623065523 DO - 10.2174/1381612822666160623065523 ID - Mateu-Jimenez2016 ER - TY - JOUR AU - Fasanaro, P. AU - D'Alessandra, Y. AU - Di, S. V. AU - Melchionna, R. AU - Romani, S. AU - Pompilio, G. PY - 2008 DA - 2008// TI - MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3 JO - J Biol Chem VL - 283 UR - https://doi.org/10.1074/jbc.M800731200 DO - 10.1074/jbc.M800731200 ID - Fasanaro2008 ER - TY - JOUR AU - Schliekelman, M. J. AU - Gibbons, D. L. AU - Faca, V. M. AU - Creighton, C. J. AU - Rizvi, Z. H. AU - Zhang, Q. PY - 2011 DA - 2011// TI - Targets of the tumor suppressor miR-200 in regulation of the epithelial-mesenchymal transition in cancer JO - Cancer Res VL - 71 UR - https://doi.org/10.1158/0008-5472.CAN-11-0964 DO - 10.1158/0008-5472.CAN-11-0964 ID - Schliekelman2011 ER - TY - JOUR AU - Zhang, J. G. AU - Wang, J. J. AU - Zhao, F. AU - Liu, Q. AU - Jiang, K. AU - Yang, G. H. PY - 2010 DA - 2010// TI - MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC) JO - Clin Chim Acta VL - 411 UR - https://doi.org/10.1016/j.cca.2010.02.074 DO - 10.1016/j.cca.2010.02.074 ID - Zhang2010 ER - TY - JOUR AU - Zhu, S. AU - Si, M. L. AU - Wu, H. AU - Mo, Y. Y. PY - 2007 DA - 2007// TI - MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1) JO - J Biol Chem VL - 282 UR - https://doi.org/10.1074/jbc.M611393200 DO - 10.1074/jbc.M611393200 ID - Zhu2007 ER - TY - JOUR AU - Trang, P. AU - Medina, P. P. AU - Wiggins, J. F. AU - Ruffino, L. AU - Kelnar, K. AU - Omotola, M. PY - 2010 DA - 2010// TI - Regression of murine lung tumors by the let-7 microRNA JO - Oncogene VL - 29 UR - https://doi.org/10.1038/onc.2009.445 DO - 10.1038/onc.2009.445 ID - Trang2010 ER - TY - JOUR AU - Wang, P. Y. AU - Sun, Y. X. AU - Zhang, S. AU - Pang, M. AU - Zhang, H. H. AU - Gao, S. Y. PY - 2013 DA - 2013// TI - Let-7c inhibits A549 cell proliferation through oncogenic TRIB2 related factors JO - FEBS Lett VL - 587 UR - https://doi.org/10.1016/j.febslet.2013.07.004 DO - 10.1016/j.febslet.2013.07.004 ID - Wang2013 ER - TY - JOUR AU - Zhao, B. AU - Han, H. AU - Chen, J. AU - Zhang, Z. AU - Li, S. AU - Fang, F. PY - 2014 DA - 2014// TI - MicroRNA let-7c inhibits migration and invasion of human non-small cell lung cancer by targeting ITGB3 and MAP4K3 JO - Cancer Lett VL - 342 UR - https://doi.org/10.1016/j.canlet.2013.08.030 DO - 10.1016/j.canlet.2013.08.030 ID - Zhao2014 ER - TY - JOUR AU - Oh, J. S. AU - Kim, J. J. AU - Byun, J. Y. AU - Kim, I. A. PY - 2010 DA - 2010// TI - Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras JO - Int J Radiat Oncol Biol Phys VL - 76 UR - https://doi.org/10.1016/j.ijrobp.2009.08.028 DO - 10.1016/j.ijrobp.2009.08.028 ID - Oh2010 ER - TY - JOUR AU - Zhong, M. AU - Ma, X. AU - Sun, C. AU - Chen, L. PY - 2010 DA - 2010// TI - MicroRNAs reduce tumor growth and contribute to enhance cytotoxicity induced by gefitinib in non-small cell lung cancer JO - Chem Biol Interact VL - 184 UR - https://doi.org/10.1016/j.cbi.2010.01.025 DO - 10.1016/j.cbi.2010.01.025 ID - Zhong2010 ER - TY - STD TI - Guzman L, Depix MS, Salinas AM, Roldan R, Aguayo F, Silva A, et al. Analysis of aberrant methylation on promoter sequences of tumor suppressor genes and total DNA in sputum samples: a promising tool for early detection of COPD and lung cancer in smokers. Diagn Pathol. 2012;7(87) https://doi.org/10.1186/1746-1596-7-87. Pubmed PMID: PMC3424112 ID - ref45 ER - TY - JOUR AU - Wang, D. C. AU - Shi, L. AU - Zhu, Z. AU - Gao, D. AU - Zhang, Y. PY - 2017 DA - 2017// TI - Genomic mechanisms of transformation from chronic obstructive pulmonary disease to lung cancer JO - Semin Cancer Biol VL - 42 UR - https://doi.org/10.1016/j.semcancer.2016.11.001 DO - 10.1016/j.semcancer.2016.11.001 ID - Wang2017 ER - TY - JOUR AU - Courtney, J. M. AU - Spafford, P. L. PY - 2017 DA - 2017// TI - The role of epithelial-mesenchymal transition in chronic obstructive pulmonary disease JO - Cells Tissues Organs VL - 203 UR - https://doi.org/10.1159/000450919 DO - 10.1159/000450919 ID - Courtney2017 ER - TY - JOUR AU - Saber, A. AU - van der Wekken, A. J. AU - Kerner, G. S. AU - van den Berge, M. AU - Timens, W. AU - Schuuring, E. PY - 2016 DA - 2016// TI - Chronic obstructive pulmonary disease is not associated with KRAS mutations in non-small cell lung cancer JO - PLoS One VL - 11 UR - https://doi.org/10.1371/journal.pone.0152317 DO - 10.1371/journal.pone.0152317 ID - Saber2016 ER - TY - JOUR AU - Tufman, A. AU - Tian, F. AU - Huber, R. M. PY - 2013 DA - 2013// TI - Can microRNAs improve the management of lung cancer patients? A clinician’s perspective JO - Theranostics VL - 3 UR - https://doi.org/10.7150/thno.6615 DO - 10.7150/thno.6615 ID - Tufman2013 ER - TY - JOUR AU - Markou, A. AU - Zavridou, M. AU - Lianidou, E. S. PY - 2016 DA - 2016// TI - miRNA-21 as a novel therapeutic target in lung cancer JO - Lung Cancer (Auckl ) VL - 7 ID - Markou2016 ER -