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Table 2 Clinical characteristics of the validation set

From: The signature of liver cancer in immune cells DNA methylation

Variable Control (n = 10) HepB (n = 10) HepC (n = 10) HCC1 (n = 8) HCC2 (n = 12) HCC3 (n = 11) HCC4 (n = 19) p value
Age (mean ± SD) 35.5 ± 7.5 43.9 ± 15.46 50.1 ± 14.7 61.75 ± 9.39 56 ± 7.45 48.09 ± 7.49 53.63 ± 9.77 5 × 10−5
Sex  
 Male 6 (60%) 7 (70%) 5 (50%) 8 (100%) 10 (83%) 11 (100%) 16 (84%)  
 Female 4 3 5 0 2 0 3  
Alcohol 8 × 10−4
 No NA 10 (100%) 9 (90%) 7 (87.5%) 8 (67%) 3 (27%) 9 (47%)  
 Quit NA 0 1 0 0 0 1  
 Infrequent NA 0 0 0 1 0 0  
 Heavy NA 0 0 1 3 8 9  
Smoking 0.035
 No NA 6 (60%) 8 80%) 4 (50%) 8 (67%) 9 (82%) 9 (47%)  
 Quit NA 1 0 0 1 0 0  
 Low NA 0 0 0 0 0 1  
 Heavy NA 3 2 4 3 2 9  
Cirrhosis 0 0 0 0 0 0 0  
Hepatitis B 0 (0%) 10 (100%) 1 (10%) 8 (100%) 12 (100%) 11 (100%) 19 (100%) 3 × 10−13
Hepatitis C 0 (0%) 0 (0%) 10 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0
AFP 0 (0%) 0 (0%) 0 (0%) 1 (12.5%) 2 (16.6%) 4 (36%) 9 (47.3%) 0.34