Table 1 Clinical characteristics of the training set
From: The signature of liver cancer in immune cells DNA methylation
Variable | Control (n = 10) | HepB (n = 10) | HepC (n = 10) | HCC1 (n = 10) | HCC2 (n = 10) | HCC3 (n = 10) | HCC4 (n = 9) | p value |
|---|---|---|---|---|---|---|---|---|
Age (mean ± SD) | 34.4 ± 8.5 | 36.9 ± 9.04 | 37.7 ± 12.08 | 52.9 ± 5.97 | 52.2 ± 12.2 | 56.1 ± 5.5 | 48 ± 15.06 | 5 × 10−6 |
Sex | 0.034 | |||||||
 Male | 3 (30%) | 8 (80%) | 7 (70%) | 9 (90%) | 8 (80%) | 9 (90%) | 7 (70%) |  |
 Female | 7 | 2 | 3 | 1 | 2 | 1 | 2 |  |
Alcohol | N.S. | |||||||
 No | 8 (80%) | 6 (60%) | 8 (80%) | 4 (40%) | 5 (50%) | 4 (40%) | 5 (50%) |  |
 Infrequent | 2 | 1 | 2 | 2 | 1 | 0 | 2 |  |
 Heavy | 0 | 3 | 0 | 4 | 4 | 6 | 2 |  |
Smoking | N.S. | |||||||
 No | 8 (80%) | 5 (50%) | 7 (70%) | 6 (60%) | 5 (50%) | 4 (40%) | 6 (60%) |  |
 Quit | 0 | 0 | 0 | 0 | 3 | 2 | 1 |  |
 Low | 0 | 0 | 0 | 0 | 1 | 0 | 0 |  |
 Heavy | 2 | 5 | 3 | 4 | 1 | 4 | 2 |  |
Cirrhosis | 0 | 0 | 0 | 0 | 0 | 0 | 0 | Â |
Hepatitis B | 0 | 10 | 0 | 10 | 9 | 10 | 8 | 2 × 10−16 |
Hepatitis C | 0 | 0 | 10 | 2 | 1 | 0 |  | 3 × 10−16 |
AFP (> 500u/ng) | 0 | 1 (10%) | 0 | 0 | 1 (10%) | 3 (30%) | 5 (50%) | 0.043 |