Skip to main content

Advertisement

Table 1 Clinical characteristics of the training set

From: The signature of liver cancer in immune cells DNA methylation

Variable Control (n = 10) HepB (n = 10) HepC (n = 10) HCC1 (n = 10) HCC2 (n = 10) HCC3 (n = 10) HCC4 (n = 9) p value
Age (mean ± SD) 34.4 ± 8.5 36.9 ± 9.04 37.7 ± 12.08 52.9 ± 5.97 52.2 ± 12.2 56.1 ± 5.5 48 ± 15.06 5 × 10−6
Sex 0.034
 Male 3 (30%) 8 (80%) 7 (70%) 9 (90%) 8 (80%) 9 (90%) 7 (70%)  
 Female 7 2 3 1 2 1 2  
Alcohol N.S.
 No 8 (80%) 6 (60%) 8 (80%) 4 (40%) 5 (50%) 4 (40%) 5 (50%)  
 Infrequent 2 1 2 2 1 0 2  
 Heavy 0 3 0 4 4 6 2  
Smoking N.S.
 No 8 (80%) 5 (50%) 7 (70%) 6 (60%) 5 (50%) 4 (40%) 6 (60%)  
 Quit 0 0 0 0 3 2 1  
 Low 0 0 0 0 1 0 0  
 Heavy 2 5 3 4 1 4 2  
Cirrhosis 0 0 0 0 0 0 0  
Hepatitis B 0 10 0 10 9 10 8 2 × 10−16
Hepatitis C 0 0 10 2 1 0   3 × 10−16
AFP (> 500u/ng) 0 1 (10%) 0 0 1 (10%) 3 (30%) 5 (50%) 0.043
  1. AFP alpha feto protein, HBV Hepatitis B virus, HCV Hepatitis C virus