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Fig. 3 | Clinical Epigenetics

Fig. 3

From: The signature of liver cancer in immune cells DNA methylation

Fig. 3

Staging of HCC using differentially methylated CGs. a Heat map presentation of hierarchical clustering of 69 people by 350 non-redundant CGs that are differentially methylated between different HCC stages and healthy controls. b Prediction of late stage HCC in 69 patients using a penalized model trained on a randomized half of the HCC patients and controls (“training set”) and tested on the other half (“validation set”). The plot shows all samples (the training and validation sets combined). The y axis indicates the predicted probability of late stage HCC for each person (from 0 to 1). c Prediction of late stages of HCC using the penalized model in T cell samples

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