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Fig. 6 | Clinical Epigenetics

Fig. 6

From: Serum microRNA array analysis identifies miR-140-3p, miR-33b-3p and miR-671-3p as potential osteoarthritis biomarkers involved in metabolic processes

Fig. 6

Diagram of relative miRNA expression levels by qRT-PCR in normal (n = 7) and osteoarthritic (OA) chondrocytes (n = 12). U6 was used for normalization of the real-time PCR data. All miRNAs appeared to be downregulated with respect to control samples. Fold change has been calculated as the log2 transformed ratio of the 2−ΔΔCt of OA samples over control samples (asterisks depict a significant difference between the 2−ΔΔCt of OA samples and 2−ΔΔCt of control samples in cartilage tissues at the p < 0.05 level). Hsa-miR-140-3p, hsa-miR-671-3p, and hsa-miR-150p were significantly downregulated in serum samples of OA patients compared to healthy individuals

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Clinical Epigenetics

ISSN: 1868-7083

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