Methylation of ZNF331 is an independent prognostic marker of colorectal cancer and promotes colorectal cancer growth

Table 2 Associations between clinicopathological features and ZNF331 methylation status in colorectal cancer patients

Clinical parameter	Number	ZNF331 methylation status		p value
Clinical parameter	Number	Methylated	Unmethylated	p value
Age(years)
≥ 60	74	52	22	0.482
< 60	72	46	26
Gender
Male	98	67	31	0.709
Female	48	31	17
Tumor differentiation
Moderate and well	106	69	37	0.436
Poor	40	29	11
TNM stage
I–II	75	47	28	0.291
III–IV	71	51	20
Tumor size
< 5 cm	75	42	33	0.005**
≥ 5 cm	71	56	15
Tumor location
Right	54	41	13	0.101
Left	92	57	35

ISSN: 1868-7083