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Table 4 Results of the longitudinal epigenome-wide association studies (EWAS)

From: Epigenome-wide association study of asthma and wheeze in childhood and adolescence

DNA methylation

Asthma definition

N [cases/controls]

Cell adjustment

FDR hits [Bonferroni]

Lambda

7.5 years

Current asthma at 16.5 years

611 [182/429]

No cells

4 [2]

1.11

Basic cells

9 [2]

1.13

Detailed cells

0 [0]

1.10

16.5 years

Current asthma at 7.5 years

784 [146/638]

No cells

28 [0]

1.24

Basic cells

1 [1]

1.16

Detailed cells

0 [0]

1.14

  1. FDR-adjusted P value and Bonferroni hits use a cut-off of < 0.05