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Table 1 Characteristics of the individuals in each EWAS model

From: Epigenome-wide association study of asthma and wheeze in childhood and adolescence

DNA methylation (outcome)

Asthma/wheeze (exposure)

Status

N

Sex [male] N (%)

Maternal age [months] mean (SD)

Maternal smoking [never] N (%)

Parity [nulliparous] N (%)

Maternal education [O-level or lower] N (%)

7.5 years

Current asthma at 7.5 years

Cases

149

88 (59%)

369 (53.4)

124 (83%)

62 (42%)

68 (46%)

Controls

632

308 (49%)

364 (51.7)

560 (89%)

286 (45%)

306 (48%)

Current wheeze at 7.5 years

Cases

111

66 (60%)

372 (55)

94 (85%)

43 (39%)

520 (45%)

Controls

742

366 (49%)

361 (52)

650 (88%)

348 (47%)

362 (49%)

16.5 years

Ever asthma at 16.5 years

Cases

194

102 (53%)

363 (53)

163 (84%)

97 (50%)

87 (45%)

Controls

554

264 (48%)

364 (51)

503 (91%)

258 (47%)

262 (47%)

Ever wheeze at 16.5 years

Cases

204

108 (53%)

367 (49)

173 (85%)

102 (50%)

82 (40%)

Controls

554

264 (48%)

363 (52)

503 (91%)

261 (47%)

271 (49%)

Current asthma at 16.5 years

Cases

184

73 (40%)

362 (51.6)

150 (82%)

89 (48%)

89 (46%)

Controls

427

200 (47%)

364 (51.7)

384 (90%)

204 (48%)

198 (46%)