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Table 1 Characteristics of the individuals in each EWAS model

From: Epigenome-wide association study of asthma and wheeze in childhood and adolescence

DNA methylation (outcome) Asthma/wheeze (exposure) Status N Sex [male] N (%) Maternal age [months] mean (SD) Maternal smoking [never] N (%) Parity [nulliparous] N (%) Maternal education [O-level or lower] N (%)
7.5 years Current asthma at 7.5 years Cases 149 88 (59%) 369 (53.4) 124 (83%) 62 (42%) 68 (46%)
Controls 632 308 (49%) 364 (51.7) 560 (89%) 286 (45%) 306 (48%)
Current wheeze at 7.5 years Cases 111 66 (60%) 372 (55) 94 (85%) 43 (39%) 520 (45%)
Controls 742 366 (49%) 361 (52) 650 (88%) 348 (47%) 362 (49%)
16.5 years Ever asthma at 16.5 years Cases 194 102 (53%) 363 (53) 163 (84%) 97 (50%) 87 (45%)
Controls 554 264 (48%) 364 (51) 503 (91%) 258 (47%) 262 (47%)
Ever wheeze at 16.5 years Cases 204 108 (53%) 367 (49) 173 (85%) 102 (50%) 82 (40%)
Controls 554 264 (48%) 363 (52) 503 (91%) 261 (47%) 271 (49%)
Current asthma at 16.5 years Cases 184 73 (40%) 362 (51.6) 150 (82%) 89 (48%) 89 (46%)
Controls 427 200 (47%) 364 (51.7) 384 (90%) 204 (48%) 198 (46%)