MicroRNA-335-5p is a potential suppressor of metastasis and invasion in gastric cancer

Clinical Epigenetics

Table 2 Deregulated genes involved in metastasis and tumor invasion in cells transfected with miR-335 mimic and inhibitor

Symbol	Name	Gene function	p value overexpressed miR-335 cells	p value inhibited miR-335 cells	References
ALDH3A1	Aldehyde dehydrogenase 3 family member A1	Oncogene	0.029	0.029	[41]
CDH11	Cadherin 11	Oncogene Tumor suppressor	0.029	0.029	[42, 43]
CLDN7	Claudin 7	Oncogene	0.029	0.029	[44]
COL4A2	Collagen type IV alpha 2	Oncogene	0.029	0.029	[45]
CST7	Cystatin F	Oncogene	0.029	0.029	[46]
CTGF	Connective tissue growth factor	Oncogene Tumor suppressor	0.029	0.027	[47, 48]
CTSK	Cathepsin K	Oncogene	0.029	0.029	[49]
HIF1A	Hypoxia inducible factor 1 alpha subunit	Oncogene	0.042	0.029	[50]
MMP7	Matrix metallopeptidase 7	Oncogene	0.029	0.029	[51]
MYC	V-myc avian myelocytomatosis viral oncogene homolog	Oncogene	0.029	0.029	[52]
NEDD9	Neural precursor cell expressed, developmentally downregulated 9	Oncogene	0.029	0.029	[53]
NF2	Neurofibromin 2 (merlin)	Oncogene Tumor suppressor	0.029	0.029	[54, 55]
PDGFA	Platelet-derived growth factor subunit A	Oncogene	0.029	0.029	[56]
PLAUR	Plasminogen activator, urokinase receptor	Oncogene	0.029	0.029	[57]
RUNX1	Runt-related transcription factor 1	Tumor suppressor Oncogene	0.029	0.029	[58, 59]
SPP1	Secreted phosphoprotein 1	Oncogene	0.029	0.027	[60]
TGFB1	Transforming growth factor beta 1	Oncogene	0.029	0.029	[61]
TIMP1	TIMP metallopeptidase inhibitor 1	Tumor suppressor Oncogene	0.029	0.029	[62]
TIMP2	TIMP metallopeptidase inhibitor 2	Tumor suppressor Oncogene	0.029	0.029	[63, 64]

ISSN: 1868-7083