Fig. 6From: Identification of a key role of widespread epigenetic drift in Barrett’s esophagus and esophageal adenocarcinomaCpG methylation transition rates based on paired longitudinal biopsies (collected at least 3–4 years apart) from the Cleveland Clinic (CC) (black) and Case Western (CW) (red). Forward (increasing) methylation transition rates represent the annual rate of CpG probes advancing past a threshold of β = 0.2, while retarding transition rates represent the fraction of CpG probes transitioning from high to low methylation (below β = 0.2)Back to article page