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Fig. 5 | Clinical Epigenetics

Fig. 5

From: Identification of a key role of widespread epigenetic drift in Barrett’s esophagus and esophageal adenocarcinoma

Fig. 5

a Typical drift patterns for BE and EAC samples by type of β value distribution. Shown are the methylation distributions for 11,425 island-associated drift CpGs (minimum of 5 drift CpGs per island). The three drift groups are based on unimodal low drift (group L), bimodal intermediate drift (group I), and bimodal high (group H). b Simulated methylation densities (arbitrary time scale) for an island-like region of 50 CpGs and 1000 cells mimicking the array-based measurements of epigenetic drift in panel a. Details provided in text

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Clinical Epigenetics

ISSN: 1868-7083

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