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Table 2 Comb-p determined differentially methylated regions (DMR)

From: Newborn genome-wide DNA methylation in association with pregnancy anxiety reveals a potential role for GABBR1

Rank comb-p

Rank DMRcate

RefGene name

Location (GRCh37/hg19 assembly)

Minimum p value

Number of probes

Stouffer-Liptak-Kechris p value

Šidák corrected

CpG island

1

624

TP53INP1

chr8:95962083–95962464

0

6

0

0

yes

2

NA

PRSS50

chr3:46759334–46759699

0

8

0

0

yes

3

3

HOXC4

chr12:54446278–54446577

0

6

0

0

no

4

169

PKP3

chr11:396685–397078

0

3

0

0

yes

5

NA

ZNF764

chr16:30572738–30573014

0

5

0

0

yes

6

2

PPT2

chr6:32120954–32121421

0

14

0

0

no

7

21

GABBR1

chr6:29595001–29595316

0

7

2.70E-07

0.07

yes

8

358

PITPNM3

chr17:6358362–6358600

0

4

2.88E-07

0.1

yes

9

NA

ESRRG

chr1:217306589–-217306764

0.01

3

1.01E-06

0.39

no

10

NA

HS3ST2

chr16:22959593–22959820

0

2

0

1

yes

  1. Both uncorrected (Stouffer-Liptak-Kechris) p values and p values corrected for multiple testing (Sidak) are shown, as well as the rank order of the DMR obtained using the DMRcate method