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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Diabetes medication associates with DNA methylation of metformin transporter genes in the human liver

Fig. 1

DNA methylation of metformin transporter genes in human liver of patients with type 2 diabetes (T2D) and non-diabetic subjects. ac Average and promoter DNA methylation according to diabetes medication (20 T2D patients receiving metformin, 10 T2D patients on insulin + metformin therapy, and 3 T2D patients on no medication) and non-diabetic subjects. P values from the ANCOVA are shown after adjusting for age, sex, and the presence of non-alcoholic steatohepatitis (NASH). Post-hoc analyses were used to compare groups: a P < 0.05 compared to non-diabetic subjects, b P < 0.05 compared to metformin treatment. Adjusted means and standard errors are shown

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