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Table 1 Phenotype data pre- and 3 months post-Roux-en-Y gastric bypass surgery
| Pre-surgery obese | Post-surgery obese | P value | |
|---|---|---|---|
| Pre vs. post | |||
| Sex | 7 female | 7 female | – |
| Age (years) | 45.1 ± 9.4 | 45.3 ± 9.3 | NS |
| Body mass index (kg/m2) | 42.1 ± 5.9 | 35.3 ± 4.9 | < 0.001 |
| Body fat (%) | 46.4 ± 3.2 | 40.6 ± 3.4 | < 0.01 |
| Systolic blood pressure (mmHg) | 125.1 ± 10.3 | 119.1 ± 12.2 | NS |
| Diastolic blood pressure (mmHg) | 71.7 ± 5.4 | 75.1 ± 4.4 | NS |
| Triglycerides (mg/dL) | 121.9 ± 46.2 | 107.7 ± 29.5 | NS |
| Cholesterol (mg/dL) | 181.4 ± 34.9 | 151.5 ± 29.6 | < 0.01 |
| High-density lipoprotein (mg/dL) | 45.0 ± 7.1 | 45.0 ± 6.7 | NS |
| Low-density lipoprotein (mg/dL) | 112.1 ± 31.6 | 84.8 ± 27.8 | < 0.01 |
| Hemoglobin A1c (%) | 6.0 ± 0.4 | 5.7 ± 0.3 | NS |
| Fasting plasma glucose (mg/dL) | 104.2 ± 20.7 | 86.7 ± 8.2 | < 0.05 |
| Fasting plasma insulin (μU/mL) | 18.2 ± 10.1 | 7.5 ± 4.2 | < 0.01 |
| EGP (mg/kg/min) | 1.5 ± 0.1 | 1.5 ± 0.1 | NS |
| M-value (mg/kg/min) | 2.4 ± 0.9 | 2.9 ± 1.0 | NS |
| M-value (mg/kgFFM/min) | 4.4 ± 1.7 | 4.9 ± 1.6 | NS |
| HOMA-IR | 4.4 ± 2.2 | 1.6 ± 0.9 | < 0.05 |
