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Table 1 Phenotype data pre- and 3 months post-Roux-en-Y gastric bypass surgery

From: Alterations of sorbin and SH3 domain containing 3 (SORBS3) in human skeletal muscle following Roux-en-Y gastric bypass surgery

  Pre-surgery obese Post-surgery obese P value
Pre vs. post
Sex 7 female 7 female
Age (years) 45.1 ± 9.4 45.3 ± 9.3 NS
Body mass index (kg/m2) 42.1 ± 5.9 35.3 ± 4.9 < 0.001
Body fat (%) 46.4 ± 3.2 40.6 ± 3.4 < 0.01
Systolic blood pressure (mmHg) 125.1 ± 10.3 119.1 ± 12.2 NS
Diastolic blood pressure (mmHg) 71.7 ± 5.4 75.1 ± 4.4 NS
Triglycerides (mg/dL) 121.9 ± 46.2 107.7 ± 29.5 NS
Cholesterol (mg/dL) 181.4 ± 34.9 151.5 ± 29.6 < 0.01
High-density lipoprotein (mg/dL) 45.0 ± 7.1 45.0 ± 6.7 NS
Low-density lipoprotein (mg/dL) 112.1 ± 31.6 84.8 ± 27.8 < 0.01
Hemoglobin A1c (%) 6.0 ± 0.4 5.7 ± 0.3 NS
Fasting plasma glucose (mg/dL) 104.2 ± 20.7 86.7 ± 8.2 < 0.05
Fasting plasma insulin (μU/mL) 18.2 ± 10.1 7.5 ± 4.2 < 0.01
EGP (mg/kg/min) 1.5 ± 0.1 1.5 ± 0.1 NS
M-value (mg/kg/min) 2.4 ± 0.9 2.9 ± 1.0 NS
M-value (mg/kgFFM/min) 4.4 ± 1.7 4.9 ± 1.6 NS
HOMA-IR 4.4 ± 2.2 1.6 ± 0.9 < 0.05
  1. Data presented as mean ± SD
  2. HOMA-IR homeostatic model assessment for insulin resistance, EGP endogenous glucose production