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Table 3 Gene expression changes and cohesin-binding status

From: The effect of Nipped-B-like (Nipbl) haploinsufficiency on genome-wide cohesin binding and target gene expression: modeling Cornelia de Lange syndrome

 

Total

Cohesin binding

Gene region

Promoter

Gene body

Downstream

None

Total

218

115

61

83

20

103

Upregulated

62

30

14

22

6

32

Downregulated

156

85

47

61

14

71

  1. (Fold change > 1.2; p value < 0.05)