Table 4 Correlation between different levels of miR-124-3 methylation and clinical parameters
Variables | No. | miR-124-3 methylation | P | |
|---|---|---|---|---|
| Â | Low-meth (n%) | High-meth (n%) | ||
Sex | Â | Â | Â | 0.150 |
 Male | 36 | 11(30.6) | 25(69.4) | |
 Female | 20 | 10(50.0) | 10(50.0) | |
Age | Â | Â | Â | 0.015 |
  < 60 | 25 | 5(20.0) | 20(80.0) | |
  ≥ 60 | 31 | 16(51.6) | 15(48.4) | |
WBC (× 109/L) |  |  |  | 1.000 |
  ≥ 4 | 13 | 5(38.5) | 8(61.5) | |
  < 4 | 43 | 16(37.2) | 27(62.8) | |
Hb(g/dL) | Â | Â | Â | 0.715 |
  ≥ 10 | 9 | 4(44.4) | 5(55.6) | |
  < 10 | 47 | 17(36.2) | 30(63.8) | |
PLT (× 109/L) |  |  |  | 0.184 |
  ≥ 100 | 18 | 9(50.0) | 9(50.0) | |
  < 100 | 38 | 12(31.6) | 26(68.4) | |
MCV(fL) | Â | Â | Â | 0.783 |
  ≥ 100 | 28 | 11(39.3) | 17(60.7) | |
  < 100 | 28 | 10(35.7) | 18(64.3) | |
WHO classification | Â | Â | Â | 0.006 |
 SLD/RS-SLD/ MDS-U/5q- | 10 | 7(70.0) | 3(30.0) | |
 MLD/RS-MLD | 10 | 6(60.0) | 4(40.0) | |
 EB-1/EB-2 | 36 | 8(22.2) | 28(77.8) | |
BM blast (%) | Â | Â | Â | 0.006 |
  < 5 | 20 | 13(65.0) | 7(35.0) | |
 5–10 | 15 | 3(20.0) | 12(80.0) | |
 11–19 | 21 | 5(23.8) | 16(76.2) | |
Cytopenias | Â | Â | Â | 0.298 |
 0/1 | 11 | 6(54.5) | 5(45.5) | |
 2/3 | 45 | 11(33.3) | 30(66.7) | |
Karyotype | Â | Â | Â | 0.888 |
 Good | 34 | 13(38.2) | 2 (61.8) | |
 Intermediate | 7 | 2(28.6) | 5(71.4) | |
 Poor | 14 | 5(35.7) | 9(64.3) | |
IPSS | Â | Â | Â | 0.358 |
 Low | 4 | 3(75.0) | 1(25.0) | |
 Int-1 | 24 | 9(37.5) | 15(62.5) | |
 Int-2 | 19 | 6(31.6) | 13(68.4) | |
 High | 8 | 2(25.0) | 6(75.0) | |