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Table 2 Leukaemia-free survival of MDS patients with different miR-124 methylation levels at CpG sites by pyrosequencing

From: Pyrosequencing quantified methylation level of miR-124 predicts shorter survival for patients with myelodysplastic syndrome

mir-124 genes Cut-off values (%) No. of patients Leukaemia-free survival (months) P
Low-meth High-meth Low-meth High-meth
miR-124-1 7.4 43 13 36.3 12.3 0.029
 miR-124-1-1 3.5 15 41 36.9 31.9 0.379
 miR-124-1-2 4.5 15 41 40.6 25.2 0.148
 miR-124-1-3 3.5 16 40 34.9 33.1 0.688
 miR-124-1-4 8.5 44 12 36.6 5.5 0.010
miR-124-2 24.8 27 29 43.1 18.0 0.001
 miR-124-2-1 11.5 23 33 40.3 23.5 0.058
 miR-124-2-2 15 26 30 42.9 18.3 0.002
 miR-124-2-3 19.5 35 21 37.2 18.0 0.083
 miR-124-2-4 16.5 35 21 38.2 18.4 0.011
 miR-124-2-5 30 24 32 44.7 18.0 0.001
miR-124-3 8.6 21 35 39.5 24.1 0.069
 miR-124-3-1 13.5 42 14 35.2 12.5 0.271
 miR-124-3-2 10.5 29 27 36.5 24.2 0.178
 miR-124-3-3 4.5 17 39 32.1 30.1 0.302
 miR-124-3-4 14.5 19 37 34.4 19.2 0.042
 miR-124-3-5 9.0 31 25 36.9 24.0 0.119
 miR-124-3-6 4.5 20 36 39.1 30.4 0.096
 miR-124-3-7 7.5 29 27 36.4 30.8 0.279
 miR-124-3-8 11.5 19 37 44.3 21.7 0.005
 miR-124-3-9 8.5 36 20 35.6 21.0 0.254
  1. Italics are statistically significant