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Table 1 Clinical features of study population

From: CpG location and methylation level are crucial factors for the early detection of oral squamous cell carcinoma in brushing samples using bisulfite sequencing of a 13-gene panel

 

Number

Sex

Median age

Smoke

Site

T status

N status

Training dataset

 OSCC

29

14 males

15 females

69 ± 13

21 non-smokers

8 smokers

8 tongue

4 floor of mouth

8 gum

5 cheek

3 palate

1 lip

11 T1

10 T2

2 T3

6 T4

28 N0

1 N1

 HGSIL

6

5 males

1 females

63 ± 18

6 non-smokers

6 tongue

  

 Healthy donors

65

32 males

33 females

58 ± 18

57 non-smokers

8 smokers

18 tongue

10 floor of mouth

12 gum

20 cheek

5 palate

  

Validation dataset

 Healthy donors

20

10 males

10 females

45 ± 9

16 non-smokers

4 smokers

20 tongue + cheek

  

 OSCC

2

1 male

1 female

61 ± 4

2 non-smokers

1 tongue

1 hard palate

1 T2

1 T1

1 N1

1 N0

 PVL

3

2 male

1 female

57 ± 6

2 non-smokers

1 smoker

2 tongue

1 cheek

  

 OLP

14

10 male

4 female

59 ± 6

11 non-smokers

3 smokers

12 cheek

2 gum