From: Altered epigenetic features in circulating nucleosomes in idiopathic pulmonary fibrosis
Nu.Q™ assay | IPF (untreated) vs healthy | |
---|---|---|
AUC | % sensitivity at 80% specificity | |
mH2A1.1 | 0.85 | 86 |
5mC | 0.83 | 78 |
HMGB1 | 0.81 | 74 |
H3K27Ac | 0.79 | 74 |
H3K9Ac | 0.77 | 61 |
H4K20Me3 | 0.70 | 50 |
pH2AX | 0.66 | 39 |
H4Pan(Ac) | 0.57 | 13 |
H3K4Me2 | 0.57 | 14 |
H3K9Me3 | 0.54 | 13 |