Table 1 Subject characteristics
From: Altered epigenetic features in circulating nucleosomes in idiopathic pulmonary fibrosis
Healthy subjects n = 27 | Untreated IPF n = 23 | Treated IPF n = 27 | |
|---|---|---|---|
Age, years | 60(9) | 72(11)** | 68(9)* |
Gender (M/F) | 14/13 | 20/3 | 19/8 |
Height, cm | 170(9) | 171(10) | 170(9) |
Weight, kg | 74(12) | 76(15) | 78(10) |
BMI, kg/m2 | 26(3) | 26(4) | 27(3) |
Smokers (NS/FS/S) | 6/17/4 | 6/13/4 | 7/20/0 |
FEV1 post-BD, %pred. | 104(14) | 75(14)*** | 67(13)*** |
FVC post-BD, %pred. | 112(20) | 74(14)*** | 66(16)*** |
FEV1/FVC post-BD, % | 78(5) | 78(11) | 80(6) |
TLC, %pred. | nd | 70(13) | 68(15) |
RV, %pred. | nd | 71(32) | 82(27) |
DLCO, %pred. | nd | 39(13) | 38(13) |
KCO, %pred. | nd | 62(13) | 70(20) |
ICS (yes/no) | 0/27 | 1/22 | 0/27 |
OCS (yes/no) | 0/27 | 0/23 | 0/27 |
Treatment with pirfenidone/nintedanib | nd | nd | 18/9 |