Fig. 2
From: Altered epigenetic features in circulating nucleosomes in idiopathic pulmonary fibrosis

A model with four cfnucleosome biomarkers discriminates IPF vs healthy patients. ROC curve for the discrimination of untreated IPF vs healthy subjects. The AUC for a model of four cfnucleosome biomarkers (HMGB1, 5mC, H3K9Ac, H3K27Ac) reached 0.928 (p < 0.001) with a sensitivity of 91% at 80% specificity