Fig. 5
From: LSD1 dual function in mediating epigenetic corruption of the vitamin D signaling in prostate cancer
Visual representation of the methylation changes observed using the Qiagen methylation arrays. A linear model was built to identify differentially methylated regions and the 95% confidence intervals calculated and plotted (blue lines); green dots show the genes whose methylation significantly differs between the selected conditions. Each quadrant reflects the results listed in Additional file 1: Table S1. a Contribution of vitamin D at basal conditions. b Contribution of LSD1 at basal conditions. c Contribution of vitamin D in knockdown conditions (shLSD1). d Contribution of LSD1 in the presence of vitamin D