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Fig. 3 | Clinical Epigenetics

Fig. 3

From: LSD1 dual function in mediating epigenetic corruption of the vitamin D signaling in prostate cancer

Fig. 3

Viability of a BC1A and b C4-2 cells as measured via cell count upon LSD1 knockdown and 1,25-D3 treatment. Each bar represents the mean of at least three biological replicates, and the Y-axis indicates the percentage of viable cells compared to the control. From left to right, in both graphs, the columns indicate shCTR + Veh, shCTR + 100 nM 1,25-D3, shLSD1 + Veh, and shLSD1 + 100 nM 1,25-D3. Statistical significance was evaluated with one-way ANOVA and Tukey post hoc correction (***p < 0.001, **p < 0.01, *p < 0.05)

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