Fig. 1From: Cooperative effect of chidamide and chemotherapeutic drugs induce apoptosis by DNA damage accumulation and repair defects in acute myeloid leukemia stem and progenitor cellsChidamide enhanced IDA, DNR, or Ara-C in cytotoxic effects on CD34+CD38− KG1α and Kasumi cells. CD34+CD38− KG1α (a) and Kasumi (b) cells were exposed to the indicated concentrations of IDA, DNR, or Ara-C with or without 0.75 μM chidamide for 24, 48, and 72 h, after which the cell viability effect was analyzed by CCK-8 assay. Percent of viability is normalized with DMSO-treated control. The values in the figure are expressed as the mean ± S.D. from three independent experimentsBack to article page