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Table 2 Gene ontology results based on top 100 ranked according to significance and effect size

From: Long-term prenatal exposure to paracetamol is associated with DNA methylation differences in children diagnosed with ADHD

Category Term Count Size P value
Increased DNA methylation
 GO:0042744 Hydrogen peroxide catabolic process 7 22 1.0 × 10−8
 GO:0072593 Reactive oxygen species metabolic process 4 209 2.1 × 10−4
 GO:0015671 Oxygen transport 2 15 2.1 × 10−5
 GO:0006898 Receptor-mediated endocytosis 4 235 3.2 × 10−4
 GO:0016192 Vesicle-mediated transport 7 877 3.3 × 10−4
 GO:0042542 Response to hydrogen peroxide 3 94 3.5 × 10−4
 GO:0016192 Bicarbonate transport 2 32 8.1 × 10−4
 GO:0006979 Response to oxidative stress 8 198 7.4 × 10−3
 GO:0055114 Oxidation-reduction process 5 837 7.2 × 10−3
Decreased DNA methylation
 GO:0050911 Detection of chemical stimulus involved in sensory perception of smell 8 248 1.0 × 10−8
 GO:0009593 Detection of chemical stimulus 6 317 1.0 × 10−8
 GO:0050906 Detection of stimulus involved in sensory perception 8 325 1.0 × 10−8
 GO:0007606 Sensory perception of chemical stimulus 6 344 1.0 × 10−8
 GO:0050877 Neurological system process 6 899 2.9 × 10−3
 GO:0004984 Olfactory receptor activity 6 247 1.0 × 10−8