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Table 2 Gene ontology results based on top 100 ranked according to significance and effect size

From: Long-term prenatal exposure to paracetamol is associated with DNA methylation differences in children diagnosed with ADHD

Category

Term

Count

Size

P value

Increased DNA methylation

 GO:0042744

Hydrogen peroxide catabolic process

7

22

1.0 × 10−8

 GO:0072593

Reactive oxygen species metabolic process

4

209

2.1 × 10−4

 GO:0015671

Oxygen transport

2

15

2.1 × 10−5

 GO:0006898

Receptor-mediated endocytosis

4

235

3.2 × 10−4

 GO:0016192

Vesicle-mediated transport

7

877

3.3 × 10−4

 GO:0042542

Response to hydrogen peroxide

3

94

3.5 × 10−4

 GO:0016192

Bicarbonate transport

2

32

8.1 × 10−4

 GO:0006979

Response to oxidative stress

8

198

7.4 × 10−3

 GO:0055114

Oxidation-reduction process

5

837

7.2 × 10−3

Decreased DNA methylation

 GO:0050911

Detection of chemical stimulus involved in sensory perception of smell

8

248

1.0 × 10−8

 GO:0009593

Detection of chemical stimulus

6

317

1.0 × 10−8

 GO:0050906

Detection of stimulus involved in sensory perception

8

325

1.0 × 10−8

 GO:0007606

Sensory perception of chemical stimulus

6

344

1.0 × 10−8

 GO:0050877

Neurological system process

6

899

2.9 × 10−3

 GO:0004984

Olfactory receptor activity

6

247

1.0 × 10−8