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Table 1 Characteristics of subjects

From: High levels of circulating folate concentrations are associated with DNA methylation of tumor suppressor and repair genes p16, MLH1, and MGMT in elderly Chileans

 

Men

(n = 77)

Women

(n = 172)

Total

(n = 249)

Age (years)a

 mean ± SD

73.5 ± 2.7

73.9 ± 3.1

73.8 ± 3.0

 95% CI

72.9–74.1

73.5–74.4

73.4–74.2

 Education (years)

 median (p25–p75)b

6 (4–8)

6 (8–3)

6 (8–3)

 ≤6 years % (n)c

56.6 (43)

63.7 (107)

61.5 (150)

 95% CI

44.7–67.9

55.9–71.0

55.1–67.6

Medication (number)***c

 0, % (n)

23.4 (18)

11.1 (19)

14.9 (37)

 95% CI

14.5–34.4

6.8–16.7

10.7–19.9

 1, % (n)

19.5 (15)

10.5 (18)

13.3 (33)

 95% CI

11.3–30.1

6.3–16.0

9.3–18.1

 2–3, % (n)

36.4 (28)

34.9 (60)

35.3 (88)

 95% CI

25.7–48.1

27.8–42.5

29.4–41.6

 4+, % (n)

20.8 (16)

43.6 (75)

36.6 (91)

 95% CI

12.4–31.5

36.1–51.4

30.5–42.9

MMSE*b

 median (p25–p75)

28 (26–29)

27 (25–29)

27 (25–29)

BMI*a

   

 BMI*a mean ± SD

26.9 ± 3.2

28.5 ± 5.1

28.1 ± 4.7

 95% CI

26.2–27. 7

27.7–29.3

27.4–28.6

Tobacco consumption**c

 % (n)

10.5 (8)

5.8 (10)

7.3 (18)

 CI 95%

4.6–19.4

2.8–10.4

4.3–11.2

  1. Medications frequently used in elderly: antihypertensive, anti-inflammatory, antidepressant
  2. BMI Body Mass Index, MMSE Minimental state examination
  3. *p < 0.05; **p < 0.01; ***p < 0.001
  4. aTwo-sample mean-comparison test
  5. bTwo-sample Wilcoxon rank-sum test
  6. cPearson’s Chi2 test
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Clinical Epigenetics

ISSN: 1868-7083

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