Fig. 3
From: Single-molecule quantification of 5-hydroxymethylcytosine for diagnosis of blood and colon cancers
a Fluorescence microscopy images of representative DNA molecules (red) with 5hmC labelling (green/yellow) extracted from healthy colon tissue, CRC, and adjacent colon tissue taken from the same patient. b Box plot comparison of 5hmC level as calculated from imaged molecules of healthy colon (n = 7), CRC (n = 7), and adjacent colon tissue (n = 7). c Fluorescence microscopy images of representative DNA molecules (red) with 5hmC labelling (green/yellow) extracted from healthy, CLL, ALL, and MM peripheral blood cells respectively. d Box plot comparison of 5hmC level as calculated from imaged molecules of healthy (n = 11), CLL (n = 8), ALL (n = 3), and MM (n = 4) peripheral blood cells