Epigenetic silencing of SALL3 is an independent predictor of poor survival in head and neck cancer

Clinical Epigenetics

Table 1 SALL3 gene methylation status in primary samples of HNSCC

Patient and tumor characteristics (n = 236)	Methylation
Patient and tumor characteristics (n = 236)	Present (n = 153)	Absent (n = 83)	P value
Age^a
70 and older (82)	56	26	0.475
Under 70 (154)	97	57	0.475
Sex^a
Male (198)	126	72	0.460
Female (38)	27	11	0.460
Smoking status^a
Smoker (174)	116	58	1
Nonsmoker (62)	37	25	1
Alcohol intake^a
Ever (172)	112	60	1
Never (64)	41	23	1
Tumor size^a
T1-2 (109)	71	38	1
T3-4 (127)	82	45	1
Lympho-node status^a
N0 (102)	67	35	0.891
N+ (134)	86	48	0.891
Stage^a
I, II, III (105)	68	37	1
IV (131)	85	46	1
HPV status
Positive (29)	18	11	1
Negative (199)	130	69	1
Indeterminate (8)

ISSN: 1868-7083