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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Effect of personal exposure to black carbon on changes in allergic asthma gene methylation measured 5 days later in urban children: importance of allergic sensitization

Fig. 2

Effects of personal BC exposure on DNA promoter region methylation 5 days later of a IL4 (CpG−326, CpG−48, b IFNγ (CpG−186, CpG−54), and c NOS2A (CpG+5099, CpG+5106), stratified by allergic sensitization. Relative risk (RR) estimates of DNA methylation of asthma genes and 95% confidence interval (CI), for a unit increase in log BC concentrations among seroatopic (♦ N = 75), non-atopic ( N = 68), cockroach-sensitized (• CR+ N = 55), and non-sensitized ( CR− N = 88) children, adjusting for race/ethnicity, sex, age, asthma diagnosis, obesity, season, and DNA methylation on day 1. *p < 0.05 and **p < 0.01

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