From: Prognostic significance of LINE-1 hypomethylation in oropharyngeal squamous cell carcinoma
Variable | Cases, n = 9 | Controls, n = 24 | p valuec | ||
---|---|---|---|---|---|
n | (%) | n | (%) | ||
Gender | |||||
Male | 4 | (44.4) | 17 | (70.8) | 0.23 |
Female | 5 | (55.6) | 7 | (29.2) | |
Age, years | |||||
<55 | 1 | (11.1) | 4 | (16.7) | 1.00 |
55–59 | 2 | (22.2) | 4 | (16.7) | |
≥60 | 6 | (66.7) | 16 | (66.7) | |
Smoking habits | |||||
Never | 3 | (33.3) | 5 | (20.8) | 0.32 |
Former | 1 | (11.1) | 1 | (4.2) | |
Current | 5 | (55.6) | 18 | (75.0) | |
Na, b | |||||
0–1 | 3 | (33.3) | 9 | (37.5) | 1.00 |
2–3 | 6 | (66.7) | 15 | (62.5) | |
Ta, b | |||||
1–2 | 3 | (33.3) | 8 | (33.3) | 1.00 |
3–4 | 6 | (66.7) | 16 | (66.7) | |
Stage | |||||
III | 2 | (22.2) | 6 | (25.0) | 1.00 |
IV | 7 | (77.8) | 18 | (75.0) | |
HPV16 | |||||
Negative | 8 | (88.9) | 12 | (50.0) | 0.06 |
Positive | 1 | (11.1) | 12 | (50.0) | |
Therapy | |||||
RT ± CT | 3 | (33.3) | 12 | (50.0) | 0.46 |
RT + CH ± CT | 6 | (66.7) | 12 | (50.0) |