Fig. 2
From: Prognostic significance of LINE-1 hypomethylation in oropharyngeal squamous cell carcinoma
LINE-1 methylation in patients who relapsed within 24 months from the end of treatment (cases) and in patients who did not (controls), according to HPV16 status, current tobacco smoking, and risk group. Risk group was defined on HPV16 status and current tobacco smoking as follow: low (HPV16+/non-smokers), intermediate (HPV16−/non-smokers or HPV16+/smokers), high (HPV16−/smokers). Black horizontal bars represent the median values of LINE-1 methylation for each group. p values were determined by the non-parametric Kruskal–Wallis test