TY - JOUR AU - Vogelstein, B. AU - Fearon, E. R. AU - Hamilton, S. R. AU - Kern, S. E. AU - Preisinger, A. C. AU - Leppert, M. PY - 1988 DA - 1988// TI - Genetic alterations during colorectal tumor development JO - N Eng J Med VL - 319 UR - https://doi.org/10.1056/NEJM198809013190901 DO - 10.1056/NEJM198809013190901 ID - Vogelstein1988 ER - TY - JOUR AU - Jass, J. R. AU - Whitehall, V. L. AU - Young, J. AU - Leggett, B. A. PY - 2002 DA - 2002// TI - Emerging concepts in colorectal neoplasia JO - Gastroenterology VL - 123 UR - https://doi.org/10.1053/gast.2002.35392 DO - 10.1053/gast.2002.35392 ID - Jass2002 ER - TY - JOUR AU - Ogino, S. AU - Goel, A. PY - 2008 DA - 2008// TI - Molecular classification and correlates in colorectal cancer JO - J Mol Diagn VL - 10 UR - https://doi.org/10.2353/jmoldx.2008.070082 DO - 10.2353/jmoldx.2008.070082 ID - Ogino2008 ER - TY - JOUR AU - Lengauer, C. AU - Kinzler, K. W. AU - Vogelstein, B. PY - 1997 DA - 1997// TI - Genetic instability in colorectal cancers JO - Nature VL - 386 UR - https://doi.org/10.1038/386623a0 DO - 10.1038/386623a0 ID - Lengauer1997 ER - TY - JOUR PY - 2012 DA - 2012// TI - Comprehensive molecular characterization of human colon and rectal cancer JO - Nature VL - 487 UR - https://doi.org/10.1038/nature11252 DO - 10.1038/nature11252 ID - ref5 ER - TY - JOUR AU - Kaneda, A. AU - Yagi, K. PY - 2011 DA - 2011// TI - Two groups of DNA methylation markers to classify colorectal cancer into three epigenotypes JO - Cancer Sci VL - 102 UR - https://doi.org/10.1111/j.1349-7006.2010.01712.x DO - 10.1111/j.1349-7006.2010.01712.x ID - Kaneda2011 ER - TY - JOUR AU - Toyota, M. AU - Ahuja, N. AU - Ohe-Toyota, M. AU - Herman, J. G. AU - Baylin, S. B. AU - Issa, J. P. PY - 1999 DA - 1999// TI - CpG island methylator phenotype in colorectal cancer JO - Proc Natl Acad Sci U S A VL - 96 UR - https://doi.org/10.1073/pnas.96.15.8681 DO - 10.1073/pnas.96.15.8681 ID - Toyota1999 ER - TY - JOUR AU - Shen, L. AU - Toyota, M. AU - Kondo, Y. AU - Lin, E. AU - Zhang, L. AU - Guo, Y. PY - 2007 DA - 2007// TI - Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer JO - Proc Natl Acad Sci U S A VL - 104 UR - https://doi.org/10.1073/pnas.0704652104 DO - 10.1073/pnas.0704652104 ID - Shen2007 ER - TY - JOUR AU - Guinney, J. AU - Dienstmann, R. AU - Wang, X. AU - Reyniès, A. AU - Schlicker, A. AU - Soneson, C. PY - 2015 DA - 2015// TI - The consensus molecular subtypes of colorectal cancer JO - Nat Med VL - 21 UR - https://doi.org/10.1038/nm.3967 DO - 10.1038/nm.3967 ID - Guinney2015 ER - TY - JOUR AU - Müller, M. F. AU - Ibrahim, A. E. AU - Arends, M. J. PY - 2016 DA - 2016// TI - Molecular pathological classification of colorectal cancer JO - Virchows Arch VL - 469 UR - https://doi.org/10.1007/s00428-016-1956-3 DO - 10.1007/s00428-016-1956-3 ID - Müller2016 ER - TY - JOUR AU - Dienstmann, R. AU - Vermeulen, L. AU - Guinney, J. AU - Kopetz, S. AU - Tejpar, S. AU - Tabernero, J. PY - 2017 DA - 2017// TI - Consensus molecular subtypes and the evolution of precision medicine in colorectal cancer JO - Nat Rev Cancer VL - 17 UR - https://doi.org/10.1038/nrc.2016.126 DO - 10.1038/nrc.2016.126 ID - Dienstmann2017 ER - TY - JOUR AU - Takahashi, Y. AU - Sugai, T. AU - Habano, W. AU - Ishida, K. AU - Eizuka, M. AU - Otsuka, K. PY - 2016 DA - 2016// TI - Molecular differences in the microsatellite stable phenotype between left-sided and right-sided colorectal cancer JO - Int J Cancer VL - 139 UR - https://doi.org/10.1002/ijc.30377 DO - 10.1002/ijc.30377 ID - Takahashi2016 ER - TY - JOUR AU - Sugai, T. AU - Habano, W. AU - Jiao, Y. -. F. AU - Tsukahara, M. AU - Takeda, Y. AU - Otsuka, K. PY - 2006 DA - 2006// TI - Analysis of molecular alterations in left- and right-sided colorectal carcinomas reveals distinct pathways of carcinogenesis: proposal for new molecular profile of colorectal carcinomas JO - J Mol Diagn VL - 8 UR - https://doi.org/10.2353/jmoldx.2006.050052 DO - 10.2353/jmoldx.2006.050052 ID - Sugai2006 ER - TY - JOUR AU - Hawthorn, L. AU - Lan, L. AU - Mojica, W. PY - 2014 DA - 2014// TI - Evidence for field effect cancerization in colorectal cancer JO - Genomics VL - 103 UR - https://doi.org/10.1016/j.ygeno.2013.11.003 DO - 10.1016/j.ygeno.2013.11.003 ID - Hawthorn2014 ER - TY - JOUR AU - Park, S. K. AU - Song, C. S. AU - Yang, H. J. AU - Jung, Y. S. AU - Choi, K. Y. AU - Koo, D. H. PY - 2016 DA - 2016// TI - Field cancerization in sporadic colon cancer JO - Gut Liver VL - 10 UR - https://doi.org/10.5009/gnl15334 DO - 10.5009/gnl15334 ID - Park2016 ER - TY - JOUR AU - Baba, Y. AU - Ishimoto, T. AU - Kurashige, J. AU - Iwatsuki, M. AU - Sakamoto, Y. AU - Yoshida, N. PY - 2016 DA - 2016// TI - Epigenetic field cancerization in gastrointestinal cancers JO - Cancer Lett VL - 375 UR - https://doi.org/10.1016/j.canlet.2016.03.009 DO - 10.1016/j.canlet.2016.03.009 ID - Baba2016 ER - TY - JOUR AU - Belshaw, N. J. AU - Pal, N. AU - Tapp, H. S. AU - Dainty, J. R. AU - Lewis, M. P. PY - 2010 DA - 2010// TI - Patterns of DNA methylation in individual colonic crypts reveal aging and cancer-related field defects in the morphologically normal mucosa JO - Carcinogenesis VL - 31 UR - https://doi.org/10.1093/carcin/bgq077 DO - 10.1093/carcin/bgq077 ID - Belshaw2010 ER - TY - JOUR AU - Subramaniam, M. M. AU - Loh, M. AU - Chan, J. Y. AU - Liem, N. AU - Lim, P. L. AU - Peng, Y. W. PY - 2014 DA - 2014// TI - The topography of DNA methylation in the non-neoplastic colonic mucosa surrounding colorectal cancers JO - Mol Carcinog VL - 53 UR - https://doi.org/10.1002/mc.21951 DO - 10.1002/mc.21951 ID - Subramaniam2014 ER - TY - JOUR AU - Kawakami, K. AU - Ruszkiewicz, A. AU - Bennett, G. AU - Moore, J. AU - Grieu, F. AU - Watanabe, G. PY - 2006 DA - 2006// TI - DNA hypermethylation in the normal colonic mucosa of patients with colorectal cancer JO - Br J Cancer VL - 94 UR - https://doi.org/10.1038/sj.bjc.6602940 DO - 10.1038/sj.bjc.6602940 ID - Kawakami2006 ER - TY - JOUR AU - Kaz, A. M. AU - Wong, C. J. AU - Dzieciatkowski, S. AU - Luo, Y. AU - Schoen, R. E. AU - Grady, W. M. PY - 2014 DA - 2014// TI - Patterns of DNA methylation in the normal colon vary by anatomical location, gender, and age JO - Epigenetics VL - 9 UR - https://doi.org/10.4161/epi.27650 DO - 10.4161/epi.27650 ID - Kaz2014 ER - TY - JOUR AU - Ramírez, N. AU - Bandrés, E. AU - Navarro, A. AU - Pons, A. AU - Jansa, S. AU - Moreno, I. PY - 2008 DA - 2008// TI - Epigenetic events in normal colonic mucosa surrounding colorectal cancer lesions JO - Eur J Cancer VL - 44 UR - https://doi.org/10.1016/j.ejca.2008.09.004 DO - 10.1016/j.ejca.2008.09.004 ID - Ramírez2008 ER - TY - JOUR AU - Qi, J. AU - Zhu, Y. Q. AU - Luo, J. AU - Tao, W. H. PY - 2006 DA - 2006// TI - Hypermethylation and expression regulation of secreted frizzled-related protein genes in colorectal tumor JO - World J Gastroenterol VL - 12 UR - https://doi.org/10.3748/wjg.v12.i44.7113 DO - 10.3748/wjg.v12.i44.7113 ID - Qi2006 ER - TY - JOUR AU - Kim, M. S. AU - Lee, J. AU - Sidransky, D. PY - 2010 DA - 2010// TI - DNA methylation markers in colorectal cancer JO - Cancer Metastasis Rev VL - 29 UR - https://doi.org/10.1007/s10555-010-9207-6 DO - 10.1007/s10555-010-9207-6 ID - Kim2010 ER - TY - JOUR AU - Kalimutho, M. AU - Cecilia, S. AU - Vecchio Blanco, G. AU - Roviello, F. AU - Sileri, P. PY - 2011 DA - 2011// TI - Epigenetically silenced miR-34b/c as a novel faecal-based screening marker for colorectal cancer JO - Br J Cancer VL - 104 UR - https://doi.org/10.1038/bjc.2011.82 DO - 10.1038/bjc.2011.82 ID - Kalimutho2011 ER - TY - JOUR AU - Abouzeid, H. E. AU - Kassem, A. M. AU - Abdel Wahab, A. H. AU - El-mezayen, H. A. AU - Sharad, H. AU - Abdel Rahman, S. PY - 2011 DA - 2011// TI - Promoter hypermethylation of RASSF1A, MGMT, and HIC-1 genes in benign and malignant colorectal tumors JO - Tumour Biol VL - 32 UR - https://doi.org/10.1007/s13277-011-0206-1 DO - 10.1007/s13277-011-0206-1 ID - Abouzeid2011 ER - TY - JOUR AU - Sahnane, N. AU - Magnoli, F. AU - Bernasconi, B. AU - Tibiletti, M. G. AU - Romualdi, C. AU - Pedroni, M. PY - 2015 DA - 2015// TI - Aberrant DNA methylation profiles of inherited and sporadic colorectal cancer JO - Clin Epigenetics VL - 7 UR - https://doi.org/10.1186/s13148-015-0165-2 DO - 10.1186/s13148-015-0165-2 ID - Sahnane2015 ER - TY - JOUR AU - Suzuki, H. AU - Igarashi, S. AU - Nojima, M. AU - Maruyama, R. AU - Yamamoto, E. AU - Kai, M. PY - 2010 DA - 2010// TI - IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype JO - Carcinogenesis VL - 31 UR - https://doi.org/10.1093/carcin/bgp179 DO - 10.1093/carcin/bgp179 ID - Suzuki2010 ER - TY - JOUR AU - Kaz, A. AU - Kim, Y. H. AU - Dzieciatkowski, S. AU - Lynch, H. AU - Watson, P. AU - Kay Washington, M. PY - 2007 DA - 2007// TI - Evidence for the role of aberrant DNA methylation in the pathogenesis of Lynch syndrome adenomas JO - Int J Cancer VL - 120 UR - https://doi.org/10.1002/ijc.22544 DO - 10.1002/ijc.22544 ID - Kaz2007 ER - TY - JOUR AU - Nakagawa, H. AU - Nuovo, G. J. AU - Zervos, E. E. AU - Martin, E. W. AU - Salovaara, R. AU - Aaltonen, L. A. PY - 2001 DA - 2001// TI - Age-related hypermethylation of the 5′ region of MLH1 in normal colonic mucosa is associated with microsatellite-unstable colorectal cancer development JO - Cancer Res VL - 61 ID - Nakagawa2001 ER - TY - JOUR AU - Toyota, M. AU - Issa, J. P. PY - 1999 DA - 1999// TI - CpG island methylator phenotypes in aging and cancer JO - Semin Cancer Biol VL - 9 UR - https://doi.org/10.1006/scbi.1999.0135 DO - 10.1006/scbi.1999.0135 ID - Toyota1999 ER - TY - BOOK PY - 2009 DA - 2009// TI - Japanese Classification of Colorectal Carcinoma, second English edition PB - Kanehara Co CY - Tokyo ID - ref31 ER - TY - JOUR AU - Habano, W. AU - Sugai, T. AU - Nakamura, S. AU - Yoshida, T. PY - 1996 DA - 1996// TI - A novel method for gene analysis of colorectal carcinomas using a crypt isolation technique JO - Lab Invest VL - 74 ID - Habano1996 ER - TY - JOUR AU - Boland, C. R. AU - Thibodeau, S. N. AU - Hamilton, S. R. AU - Sidransky, D. AU - Eshleman, J. R. AU - Burt, R. W. PY - 1998 DA - 1998// TI - National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer JO - Cancer Res VL - 58 ID - Boland1998 ER - TY - JOUR AU - Yamamoto, E. AU - Suzuki, H. AU - Yamano, H. O. AU - Maruyama, R. AU - Nojima, M. AU - Kamimae, S. PY - 2012 DA - 2012// TI - Molecular dissection of premalignant colorectal lesions reveals early onset of the CpG island methylator phenotype JO - Am J Pathol VL - 181 UR - https://doi.org/10.1016/j.ajpath.2012.08.007 DO - 10.1016/j.ajpath.2012.08.007 ID - Yamamoto2012 ER - TY - JOUR AU - Menigatti, M. AU - Truninger, K. AU - Gebbers, J. O. AU - Marbet, U. AU - Marra, G. AU - Schär, P. PY - 2009 DA - 2009// TI - Normal colorectal mucosa exhibits sex- and segment-specific susceptibility to DNA methylation at the hMLH1 and MGMT promoters JO - Oncogene VL - 28 UR - https://doi.org/10.1038/onc.2008.444 DO - 10.1038/onc.2008.444 ID - Menigatti2009 ER - TY - JOUR AU - Worthley, D. L. AU - Whitehall, V. L. AU - Buttenshaw, R. L. AU - Irahara, N. AU - Greco, S. A. AU - Ramsnes, I. PY - 2010 DA - 2010// TI - DNA methylation within the normal colorectal mucosa is associated with pathway-specific predisposition to cancer JO - Oncogene VL - 29 UR - https://doi.org/10.1038/onc.2009.449 DO - 10.1038/onc.2009.449 ID - Worthley2010 ER - TY - JOUR AU - Moretto, R. AU - Cremolini, C. AU - Rossini, D. AU - Pietrantonio, F. AU - Battaglin, F. AU - Mennitto, A. PY - 2016 DA - 2016// TI - Location of primary tumor and benefit from anti-epidermal growth factor receptor monoclonal antibodies in patients with RAS and BRAF wild-type metastatic colorectal cancer JO - Oncologist VL - 21 UR - https://doi.org/10.1634/theoncologist.2016-0084 DO - 10.1634/theoncologist.2016-0084 ID - Moretto2016 ER - TY - JOUR AU - Shen, L. AU - Kondo, Y. AU - Rosner, G. L. AU - Xiao, L. AU - Hernandez, N. S. AU - Vilaythong, J. AU - Houlihan, P. S. AU - Krouse, R. S. AU - Prasad, A. R. AU - Einspahr, J. G. AU - Buckmeier, J. AU - Alberts, D. S. AU - Hamilton, S. R. AU - Issa, J. P. PY - 2005 DA - 2005// TI - MGMT promoter methylation and field defect in sporadic colorectal cancer JO - J Natl Cancer Inst VL - 97 UR - https://doi.org/10.1093/jnci/dji275 DO - 10.1093/jnci/dji275 ID - Shen2005 ER - TY - JOUR AU - Zhang, D. AU - Bai, Y. AU - Ge, Q. AU - Qiao, Y. AU - Wang, Y. AU - Chen, Z. PY - 2006 DA - 2006// TI - Microarray-based molecular margin methylation pattern analysis in colorectal carcinoma JO - Anal Biochem VL - 355 UR - https://doi.org/10.1016/j.ab.2006.04.048 DO - 10.1016/j.ab.2006.04.048 ID - Zhang2006 ER - TY - JOUR AU - Patai, A. V. AU - Valcz, G. AU - Hollósi, P. AU - Kalmár, A. AU - Péterfia, B. AU - Patai, A. PY - 2015 DA - 2015// TI - Comprehensive DNA methylation analysis reveals a common ten-gene methylation signature in colorectal adenomas and carcinomas JO - PLoS One VL - 10 UR - https://doi.org/10.1371/journal.pone.0133836 DO - 10.1371/journal.pone.0133836 ID - Patai2015 ER -