Table 4 Epigenetic profiles of circulating nucleosomes, AUC, and sensitivity at 90% specificity
From: Circulating nucleosomes as new blood-based biomarkers for detection of colorectal cancer
Cancer vs. healthy | ||
|---|---|---|
AUC | Sensitivity at 90% specificity | |
H2AK119Ub | 0.76 | 39% |
H3K9me3 | 0.65 | 17% |
EZH2 | 0.66 | 0% |
H3K9Ac | 0.58 | 13% |
H3K27Ac | 0.58 | 0% |
H4pan Ac | 0.57 | 0% |
pH2AX | 0.57 | 0% |
5mC | 0.55 | 9% |
H4K20me3 | 0.53 | 0% |
HMGB1 | 0.53 | 0% |
Nucleosome | 0.53 | 0% |
H2AZ | 0.51 | 0% |
CEA | 0.66 | 35% |