Fig. 2
From: Circulating nucleosomes as new blood-based biomarkers for detection of colorectal cancer
ROC curves for discrimination of cancer vs. healthy controls. The area under the curve (AUC) for the established tumor marker CEA (0.66) was improved by using the best combination of four cf-nucleosome biomarkers (0.87); or the panel of four-cf-nucleosome biomarker panel with CEA (0.87). The AUC was further increased by using the age-adjusted four-cf-nucleosome panel (0.97); the gray line indicates random chance