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Table 1 Association of DIRAS1 methylation with clinicopathologic features in colorectal tumor

From: Methylation of DIRAS1 promotes colorectal cancer progression and may serve as a marker for poor prognosis

Clinical factor

DIRAS1 methylation status

P value

Unmethylated

Methylated

Gender

  

0.72

 Male

53

45

 

 Female

24

24

 

Age (year)

  

0.51

 >60

40

40

 

 ≤60

37

29

 

Tumor size (cm)

  

0.86

 >5

51

44

 

 ≤5

26

25

 

Differentiation

   

 Well

1

1

0.88

 Moderate

60

44

 

 Poor

16

24

 

Tumor invasion

  

0.12

 T1

0

0

 

 T2

16

6

 

 T3

58

59

 

 T4

3

4

 

Lymph node metastasis

  

0.07

 N0

48

32

 

 N1

29

37

 

TNM stage

  

0.02*

 I-II

47

28

 

 III-IV

30

41

 
  1. Chi-square test; *P < 0.05
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Clinical Epigenetics

ISSN: 1868-7083

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